Cellosaurus cell line H4AzC2 (CVCL

Cellosaurus H4AzC2 (CVCL_X358)

Cross-references
Cell line name	H4AzC2
Accession	CVCL_X358
Resource Identification Initiative	To cite this cell line use: H4AzC2 (RRID:CVCL_X358)
Comments	Selected for resistance to: ChEBI; CHEBI_63486; 8-azaguanine. Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE). Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease	Rat hepatocellular carcinoma (NCIt: C60416)
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: AxC; RS=RS_0000369.
Originate from same individual	CVCL_4623 ! H4-II
Sex of cell	Male
Category	Cancer cell line
Publications	PubMed=28957; DOI=10.1016/0014-4827(78)90280-X Leslie Anne Leinwand, Roger Kurt Strair, Francis Hugh Ruddle; Phenotypic and molecular expression of albumin in rat hepatoma x L cell hybrids. Exp. Cell Res. 115:261-268(1978) PubMed=203590; DOI=10.1016/S0021-9258(17)34868-8 Roger Kurt Strair, Sing Hiem Yap, Bernardo Nadal-Ginard, David A. Shafritz; Identification of a high molecular weight presumptive precursor to albumin mRNA in the nucleus of rat liver and hepatoma cell line H4AZC2. J. Biol. Chem. 253:1328-1331(1978) PubMed=9745712; DOI=10.1111/j.1432-0436.1998.00215.x Isabel Zvibel, Anthony S. Fiorino, Shlomo Brill, Lola M. Reid; Phenotypic characterization of rat hepatoma cell lines and lineage-specific regulation of gene expression by differentiation agents. Differentiation 63:215-223(1998)
Encyclopedic resources	Wikidata; Q54872155
Entry history
Entry creation	17-Jul-2014
Last entry update	10-Apr-2025
Version number	10