Cellosaurus cell line LAPC4-SL (CVCL

Cellosaurus LAPC4-SL (CVCL_WZ26)

Cross-references
Cell line name	LAPC4-SL
Synonyms	Stem-Like LAPC4; LAPC4-Stem Like
Accession	CVCL_WZ26
Resource Identification Initiative	To cite this cell line use: LAPC4-SL (RRID:CVCL_WZ26)
Comments	Characteristics: Reprogrammed to, maintained and propagated as cancer stem-like cells (CSCs) by growth in androgen-free neural/neural crest (N/NC) stem medium. Virology: Contains an integrated xenotropic MuLV-related virus (XMRV) Bxv-1 (from parent cell line). Omics: Transcriptomics; Microarray. Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (from parent cell line).
Disease	Prostate carcinoma (NCIt: C4863)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_4744 (LAPC-4)
Sex of cell	Male
Age at sampling	Age unspecified
Category	Cancer cell line
Publications	PubMed=28145883; DOI=10.18632/oncotarget.14850; PMCID=PMC5386661 Mannan Nouri, Josselin Caradec, Amy Anne Lubik, Na Li, Brett G. Hollier, Mandeep Takhar, Manuel Altimirano-Dimas, Meng-Qian Chen, Mani Roshan-Moniri, Miriam Butler, Melanie Lehman ...Show all 27 authors... , Jennifer L. Bishop, Sarah Truong, Shih-Chieh Huang, Dawn R. Cochrane, Michael Cox, Catherine Collins, Martin E. Gleave, Nicholas Erho, Mohamed Alshalafa, Elai Davicioni, Colleen Nelson, Cheryl Y. Gregory-Evans, R. Jeffrey Karnes, Robert Brian Jenkins, Eric A. Klein, Ralph Buttyan; Show fewer authors Therapy-induced developmental reprogramming of prostate cancer cells and acquired therapy resistance. Oncotarget 8:18949-18967(2017)
Cell line databases/resources	cancercelllines; CVCL_WZ26
Encyclopedic resources	Wikidata; Q95981289
Gene expression databases	GEO; GSM1633308 GEO; GSM1633309 GEO; GSM1633310
Entry history
Entry creation	06-Sep-2019
Last entry update	10-Apr-2025
Version number	11