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Cellosaurus SNU-16alpha5 (CVCL_WY38)

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Cell line name SNU-16alpha5
Synonyms SNU16alpha5; SNU16a5
Accession CVCL_WY38
Resource Identification Initiative To cite this cell line use: SNU-16alpha5 (RRID:CVCL_WY38)
Comments Population: Korean.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6141; ITGA5.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations
  • Gene fusion; HGNC; HGNC:1681; CD44 + HGNC; HGNC:10940; SLC1A2; Name(s)=CD44-SLC1A2 (from parent cell line).
  • Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Lys1358fs*2 (c.4065_4066insTTGA); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:667; RHOA; Simple; p.Arg5Trp (c.13C>T); ClinVar=VCV003765045; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:667; RHOA; Simple; p.Phe39Leu (c.117T>G); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr205Phe (c.614A>T); ClinVar=VCV000376682; Zygosity=Homozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0076 (SNU-16)
Sex of cell Female
Age at sampling 33Y
Category Cancer cell line
Publications

PubMed=14720123; DOI=10.1042/bj20031408; PMCID=PMC1224061
Hwang-Phill Kim, Mi-Sook Lee, Jiyon Yu, Jin-Ah Park, Hyun-Soon Jong, Tae-You Kim, Jung Weon Lee, Yung-Jue Bang;
TGF-beta1 (transforming growth factor-beta1)-mediated adhesion of gastric carcinoma cells involves a decrease in Ras/ERKs (extracellular-signal-regulated kinases) cascade activity dependent on c-Src activity.
Biochem. J. 379:141-150(2004)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WY38
Encyclopedic resources Wikidata; Q98132717
Entry history
Entry creation06-Sep-2019
Last entry update14-Aug-2025
Version number11