ID   SNU-16alpha5
AC   CVCL_WY38
SY   SNU16alpha5; SNU16a5
DR   cancercelllines; CVCL_WY38
DR   Wikidata; Q98132717
RX   PubMed=14720123;
CC   Population: Korean.
CC   Sequence variation: Gene fusion; HGNC; HGNC:1681; CD44 + HGNC; HGNC:10940; SLC1A2; Name(s)=CD44-SLC1A2 (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Lys1358fs*2 (c.4065_4066insTTGA); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:667; RHOA; Simple; p.Arg5Trp (c.13C>T); ClinVar=VCV003765045; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:667; RHOA; Simple; p.Phe39Leu (c.117T>G); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr205Phe (c.614A>T); ClinVar=VCV000376682; Zygosity=Homozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6141; ITGA5.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4004; Gastric adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0076 ! SNU-16
SX   Female
AG   33Y
CA   Cancer cell line
DT   Created: 06-09-19; Last updated: 14-08-25; Version: 11
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RX   PubMed=14720123; DOI=10.1042/bj20031408; PMCID=PMC1224061;
RA   Kim, Hwang-Phill
RA   Lee, Mi-Sook
RA   Yu, Jiyon
RA   Park, Jin-Ah
RA   Jong, Hyun-Soon
RA   Kim, Tae-You
RA   Lee, Jung Weon
RA   Bang, Yung-Jue
RT   "TGF-beta1 (transforming growth factor-beta1)-mediated adhesion of
RT   gastric carcinoma cells involves a decrease in Ras/ERKs
RT   (extracellular-signal-regulated kinases) cascade activity dependent on
RT   c-Src activity.";
RL   Biochem. J. 379:141-150(2004).
//