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Cellosaurus Lk9dL (CVCL_WX07)

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Cell line name Lk9dL
Synonyms LK9d(L); Lk 9 dL
Accession CVCL_WX07
Resource Identification Initiative To cite this cell line use: Lk9dL (RRID:CVCL_WX07)
Comments Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Mutation; RGD; 3908; Tsc2; Simple; p.Val1272fs; Zygosity=Heterozygous; Note=Insertion of a 5 kb retrotransposon (from autologous cell line Lk9dR).
Disease Carcinoma of the rat kidney (NCIt: C64111)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Eker x Long-Evans; RS=RS_0000385+RS_0000347.
Hierarchy Children:
CVCL_WX09 (S-Lk9d-SLM)
Originate from same individual CVCL_WX08 ! Lk9dR
Category Cancer cell line
Publications

PubMed=9914777; DOI=10.1111/j.1349-7006.1998.tb00503.x; PMCID=PMC5921719
Tomokazu Fukuda, Youko Hirayama, Hiroaki Mitani, Hiroshi Maeda, Masahiro Tsutsumi, Yoichi Konishi, Okio Hino;
Generation of metastatic variants of Eker renal carcinoma cell lines for experimental investigation of renal cancer metastasis.
Jpn. J. Cancer Res. 89:1104-1108(1998)

PubMed=11011112; DOI=10.1111/j.1349-7006.2000.tb01027.x; PMCID=PMC5926447
Shuichi Majima, Kazunori Kajino, Tomokazu Fukuda, Fujio Otsuka, Okio Hino;
A novel gene 'Niban' upregulated in renal carcinogenesis: cloning by the cDNA-amplified fragment length polymorphism approach.
Jpn. J. Cancer Res. 91:869-874(2000)

PubMed=11115552; DOI=10.3892/ijo.18.1.147
Toshihiro Okamoto, Shuji Momose, Okio Hino;
Suppression of cytochrome P450 1A1 and 4A1 gene expression in renal carcinomas of TSC2 gene mutant (Eker) rats.
Int. J. Oncol. 18:147-149(2001)

Cross-references
Encyclopedic resources Wikidata; Q95982402
Entry history
Entry creation06-Sep-2019
Last entry update10-Apr-2025
Version number8