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Cellosaurus LNCaP-19 (CVCL_WW88)

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Cell line name LNCaP-19
Synonyms LNCaP cells from passage 19
Accession CVCL_WW88
Resource Identification Initiative To cite this cell line use: LNCaP-19 (RRID:CVCL_WW88)
Comments Population: Caucasian.
Characteristics: Androgen-independent.
Doubling time: 46 hours (PubMed=15389782); 50.00 hours (JWGray panel).
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1379 (LNCaP clone FGC)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=15389782; DOI=10.1002/pros.20145
Helene Gustavsson, Karin Welen, Jan-Erik Damber;
Transition of an androgen-dependent human prostate cancer cell line into an androgen-independent subline is associated with increased angiogenesis.
Prostate 62:364-373(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WW88
Encyclopedic resources Wikidata; Q95982755
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number11