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Cellosaurus RC.SVtsA58 (CVCL_WW31)

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Cell line name RC.SVtsA58
Synonyms Renal Cortical.SV40 tsA58 transformed
Accession CVCL_WW31
Resource Identification Initiative To cite this cell line use: RC.SVtsA58 (RRID:CVCL_WW31)
Comments Characteristics: Exhibits rapid cell growth at the permissive temperature (33 Celsius). Growth is totally inhibited within 48 hours when cells are shifted to the restrictive temperature (39.5 Celsius).
Doubling time: 53.5 +- 2.4 hours (Note=At 33 Celsius) (PubMed=1709172).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Kidney, proximal tubule; UBERON=UBERON_0004134.
Species of origin Oryctolagus cuniculus (Rabbit) (NCBI Taxonomy: 9986)
Breed/subspecies: New Zealand white; VBO=VBO_0001267.
Sex of cell Male
Age at sampling <6M
Category Conditionally immortalized cell line
Publications

PubMed=1645927; DOI=10.1016/S0272-6386(12)80334-9
Alain Vandewalle, Pierre M. Ronco, Roland Cassingena;
Establishment of permanent renal tubule cell lines by infection with the wild-type and a thermosensitive mutant of the simian virus 40.
Am. J. Kidney Dis. 17:619-621(1991)

PubMed=1709172; DOI=10.1083/jcb.113.4.951; PMCID=PMC2288981
Dominique Prie, Pierre M. Ronco, Beatrice Baudouin, Monique Geniteau-Legendre, Martine Antoine, Remi Piedagnel, Simone Estrade, Brigitte Lelongt, Pierre J. Verroust, Roland Cassingena, Alain Vandewalle;
Activation of the simian virus 40 (SV40) genome abrogates sensitivity to AVP in a rabbit collecting tubule cell line by repressing membrane expression of AVP receptors.
J. Cell Biol. 113:951-962(1991)

PubMed=8023893; DOI=10.1152/ajpcell.1994.266.6.C1628
Dominique Prie, Jean-Claude Dussaule, Brigitte Lelongt, Monique Geniteau-Legendre, Francois Chatelet, Roland Cassingena, Alain Vandewalle, Pierre M. Ronco;
Principal cell-specific antigen and hormonal regulatory network in RC.SVtsA58 cell line.
Am. J. Physiol. 266:C1628-C1638(1994)

Cross-references
Encyclopedic resources Wikidata; Q98128859
Entry history
Entry creation06-Sep-2019
Last entry update19-Dec-2024
Version number8