ID   RC.SVtsA58
AC   CVCL_WW31
SY   Renal Cortical.SV40 tsA58 transformed
DR   Wikidata; Q98128859
RX   PubMed=1645927;
RX   PubMed=1709172;
RX   PubMed=8023893;
CC   Characteristics: Exhibits rapid cell growth at the permissive temperature (33 Celsius). Growth is totally inhibited within 48 hours when cells are shifted to the restrictive temperature (39.5 Celsius).
CC   Doubling time: 53.5 +- 2.4 hours (Note=At 33 Celsius) (PubMed=1709172).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
CC   Derived from site: In situ; Kidney, proximal tubule; UBERON=UBERON_0004134.
CC   Breed/subspecies: New Zealand white; VBO=VBO_0001267.
OX   NCBI_TaxID=9986; ! Oryctolagus cuniculus (Rabbit)
SX   Male
AG   <6M
CA   Conditionally immortalized cell line
DT   Created: 06-09-19; Last updated: 19-12-24; Version: 8
//
RX   PubMed=1645927; DOI=10.1016/S0272-6386(12)80334-9;
RA   Vandewalle A., Ronco P.M., Cassingena R.;
RT   "Establishment of permanent renal tubule cell lines by infection with
RT   the wild-type and a thermosensitive mutant of the simian virus 40.";
RL   Am. J. Kidney Dis. 17:619-621(1991).
//
RX   PubMed=1709172; DOI=10.1083/jcb.113.4.951; PMCID=PMC2288981;
RA   Prie D., Ronco P.M., Baudouin B., Geniteau-Legendre M., Antoine M.,
RA   Piedagnel R., Estrade S., Lelongt B., Verroust P.J., Cassingena R.,
RA   Vandewalle A.;
RT   "Activation of the simian virus 40 (SV40) genome abrogates sensitivity
RT   to AVP in a rabbit collecting tubule cell line by repressing membrane
RT   expression of AVP receptors.";
RL   J. Cell Biol. 113:951-962(1991).
//
RX   PubMed=8023893; DOI=10.1152/ajpcell.1994.266.6.C1628;
RA   Prie D., Dussaule J.-C., Lelongt B., Geniteau-Legendre M., Chatelet F.,
RA   Cassingena R., Vandewalle A., Ronco P.M.;
RT   "Principal cell-specific antigen and hormonal regulatory network in
RT   RC.SVtsA58 cell line.";
RL   Am. J. Physiol. 266:C1628-C1638(1994).
//