Cellosaurus cell line SJG-13 (CVCL

Cellosaurus SJG-13 (CVCL_WV10)

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Cell line name

SJG-13

Synonyms

SJG-013

Accession

CVCL_WV10

Resource Identification Initiative

To cite this cell line use: SJG-13 (RRID:CVCL_WV10)

Comments

Omics: Genomics; Whole exome sequencing.
Miscellaneous: STR profile from personal communication of Broad, Simon.
Derived from site: In situ; Oral cavity, alveolar ridge; UBERON=UBERON_0004103.

Sequence variations

Mutation; HGNC; HGNC:1509; CASP8; Simple; p.Ser115Ter (c.698C>A) (p.Ser174Ter, c.521C>A); Zygosity=Unspecified (PubMed=27693639).
Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012602; Zygosity=Unspecified (PubMed=27693639).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Asp (c.658T>G); ClinVar=VCV000376689; Zygosity=Unspecified (PubMed=27693639).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp259His (c.775G>C); ClinVar=VCV001349622; Zygosity=Unspecified (PubMed=27693639).

Disease

Alveolar ridge squamous cell carcinoma (NCIt: C170774)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

54Y

Category

Cancer cell line

STR profile

Source(s): Direct_author_submission

Markers:

Amelogenin	X
CSF1PO	11,12
D3S1358	14,18
D5S818	11,12
D7S820	9,11
D8S1179	12,13
D13S317	11,12
D16S539	12
D18S51	13,18
D21S11	29
FGA	21,22
Penta D	10
Penta E	12
TH01	6,9.3
TPOX	8
vWA	14,18

Publications

CLPUB00518
Stephen J. Goldie;
Studies of FRMD4A in two models of squamous cell carcinoma.
Thesis PhD (2011); University of Cambridge; Cambridge; United Kingdom

PubMed=27693639; DOI=10.1016/j.canlet.2016.09.014; PMCID=PMC5090049
Tyler F. Hayes, Nathan Benaich, Stephen J. Goldie, Kalle Sipila, Ashley Ames-Draycott, Wen-Jun Cai, Guang-Liang Yin, Fiona Mary Watt;
Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation.
Cancer Lett. 383:106-114(2016)

CLPUB00517
Ashley Jane Pritchard;
Correlating genetic change with changes in cell behaviour in squamous cell carcinoma of the head and neck (SCCHN). Focus on inactivating NOTCH1 mutations.
Thesis PhD (2018); King's College London; London; United Kingdom

Cross-references

Cell line databases/resources

cancercelllines; CVCL_WV10

Encyclopedic resources

Wikidata; Q98132581

Entry history

Entry creation

05-Jul-2019

Last entry update

10-Apr-2025

Version number