ID   SJG-13
AC   CVCL_WV10
SY   SJG-013
DR   cancercelllines; CVCL_WV10
DR   Wikidata; Q98132581
RX   CelloPub=CLPUB00517;
RX   CelloPub=CLPUB00518;
RX   PubMed=27693639;
CC   Sequence variation: Mutation; HGNC; HGNC:1509; CASP8; Simple; p.Ser115Ter (c.698C>A) (p.Ser174Ter, c.521C>A); Zygosity=Unspecified (PubMed=27693639).
CC   Sequence variation: Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012602; Zygosity=Unspecified (PubMed=27693639).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr220Asp (c.658T>G); ClinVar=VCV000376689; Zygosity=Unspecified (PubMed=27693639).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp259His (c.775G>C); ClinVar=VCV001349622; Zygosity=Unspecified (PubMed=27693639).
CC   Omics: Genomics; Whole exome sequencing.
CC   Miscellaneous: STR profile from personal communication of Broad, Simon.
CC   Derived from site: In situ; Oral cavity, alveolar ridge; UBERON=UBERON_0004103.
ST   Source(s): Direct_author_submission
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 11,12
ST   D16S539: 12
ST   D18S51: 13,18
ST   D21S11: 29
ST   D3S1358: 14,18
ST   D5S818: 11,12
ST   D7S820: 9,11
ST   D8S1179: 12,13
ST   FGA: 21,22
ST   Penta D: 10
ST   Penta E: 12
ST   TH01: 6,9.3
ST   TPOX: 8
ST   vWA: 14,18
DI   NCIt; C170774; Alveolar ridge squamous cell carcinoma
DI   ORDO; Orphanet_502363; Squamous cell carcinoma of the oral cavity
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   54Y
CA   Cancer cell line
DT   Created: 05-07-19; Last updated: 10-04-25; Version: 13
//
RX   CelloPub=CLPUB00517;
RA   Pritchard A.J.;
RT   "Correlating genetic change with changes in cell behaviour in squamous
RT   cell carcinoma of the head and neck (SCCHN). Focus on inactivating
RT   NOTCH1 mutations.";
RL   Thesis PhD (2018); King's College London; London; United Kingdom.
//
RX   CelloPub=CLPUB00518;
RA   Goldie S.J.;
RT   "Studies of FRMD4A in two models of squamous cell carcinoma.";
RL   Thesis PhD (2011); University of Cambridge; Cambridge; United Kingdom.
//
RX   PubMed=27693639; DOI=10.1016/j.canlet.2016.09.014; PMCID=PMC5090049;
RA   Hayes T.F., Benaich N., Goldie S.J., Sipila K., Ames-Draycott A.,
RA   Cai W.-J., Yin G.-L., Watt F.M.;
RT   "Integrative genomic and functional analysis of human oral squamous
RT   cell carcinoma cell lines reveals synergistic effects of FAT1 and
RT   CASP8 inactivation.";
RL   Cancer Lett. 383:106-114(2016).
//