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Cellosaurus UCD-Mel-N-PEDF (CVCL_WS25)

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Cell line name UCD-Mel-N-PEDF
Synonyms UCD-PEDF
Accession CVCL_WS25
Resource Identification Initiative To cite this cell line use: UCD-Mel-N-PEDF (RRID:CVCL_WS25)
Comments Characteristics: Stably transduced with a pLZR-PEDF-IRES-EGFP construct (PubMed=15313901).
Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:8824; SERPINF1.
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_WS21 (UCD-Mel-N)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=15313901; DOI=10.1158/0008-5472.CAN-04-0230
Marta Garcia, Nuria Isabel Fernandez-Garcia, Veronica Rivas, Marta Carretero, Maria Jose Escamez, Alicia Gonzalez-Martin, Estela E. Medrano, Olga V. Volpert, Jose Luis Jorcano, Benilde Jimenez, Fernando Larcher, Marcela Del Rio Nechaevsky;
Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor.
Cancer Res. 64:5632-5642(2004)

PubMed=21673604; DOI=10.1097/CMR.0b013e32834495c3; PMCID=PMC3131479
Jose L. Orgaz, Alberto Benguria, Cristina Sanchez-Martinez, Omar Ladhani, Olga V. Volpert, Benilde Jimenez;
Changes in the gene expression profile of A375 human melanoma cells induced by overexpression of multifunctional pigment epithelium-derived factor.
Melanoma Res. 21:285-297(2011)

Cross-references
Encyclopedic resources Wikidata; Q98133834
Entry history
Entry creation05-Jul-2019
Last entry update14-Aug-2025
Version number7