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Cellosaurus UCD-Mel-N (CVCL_WS21)

[Text version]
Cell line name UCD-Mel-N
Synonyms UCD Mel N
Accession CVCL_WS21
Resource Identification Initiative To cite this cell line use: UCD-Mel-N (RRID:CVCL_WS21)
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_WS22 (UCD-Mel-N(Ski+))CVCL_WS24 (UCD-Mel-N-GFP)CVCL_WS25 (UCD-Mel-N-PEDF)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=10811875; DOI=10.1073/pnas.090097797; PMCID=PMC18535
Wei-Dong Xu, Konstantina Angelis, David Danielpour, Maher M. Haddad, Oliver Bischof, Judith Campisi, Ed Stavnezer, Estela E. Medrano;
Ski acts as a co-repressor with Smad2 and Smad3 to regulate the response to type beta transforming growth factor.
Proc. Natl. Acad. Sci. U.S.A. 97:5924-5929(2000)

PubMed=11719430
Jon A. Reed, Elise S. Bales, Wei-Dong Xu, Nihal A. Okan, Debdutta Bandyopadhyay, Estela E. Medrano;
Cytoplasmic localization of the oncogenic protein Ski in human cutaneous melanomas in vivo: functional implications for transforming growth factor beta signaling.
Cancer Res. 61:8074-8078(2001)

PubMed=14583455
Da-Hu Chen, Wei-Dong Xu, Elise S. Bales, Clemencia Colmenares, Maralice Conacci-Sorrell, Shunsuke Ishii, Ed Stavnezer, Judith Campisi, David Erich Fisher, Avri Ben-Ze'ev, Estela E. Medrano;
SKI activates Wnt/beta-catenin signaling in human melanoma.
Cancer Res. 63:6626-6634(2003)

PubMed=15313901; DOI=10.1158/0008-5472.CAN-04-0230
Marta Garcia, Nuria Isabel Fernandez-Garcia, Veronica Rivas, Marta Carretero, Maria Jose Escamez, Alicia Gonzalez-Martin, Estela E. Medrano, Olga V. Volpert, Jose Luis Jorcano, Benilde Jimenez, Fernando Larcher, Marcela Del Rio Nechaevsky;
Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor.
Cancer Res. 64:5632-5642(2004)

Cross-references
Encyclopedic resources Wikidata; Q98133829
Entry history
Entry creation05-Jul-2019
Last entry update14-Aug-2025
Version number4