| Cell line name |
HT-29KM |
|---|
| Synonyms |
HT29KM |
|---|
| Accession |
CVCL_WN77 |
|---|
| Resource Identification Initiative |
To cite this cell line use: HT-29KM (RRID:CVCL_WN77) |
|---|
| Comments |
Population: Caucasian.
Characteristics: Established from parent cell line by passages in BALB/c nude mice.
Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
|---|
| Sequence variations |
- Mutation; HGNC; HGNC:583; APC; Simple; p.Glu853Ter (c.2557G>T); ClinVar=VCV001071632; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs*3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Pro449Thr (c.1345C>A); ClinVar=VCV001333250; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:6770; SMAD4; Simple; p.Gln311Ter (c.931C>T); ClinVar=VCV000230663; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
|
|---|
| Disease |
Colon adenocarcinoma (NCIt: C4349) |
|---|
| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
|---|
| Hierarchy |
Parent: CVCL_0320 (HT-29) |
|---|
| Sex of cell |
Female |
|---|
| Age at sampling |
44Y |
|---|
| Category |
Cancer cell line |
|---|
| Publications | PubMed=1730571; DOI=10.1007/BF02631079
Thomas J. Goodwin, John Milburn Jessup, David Alexander Wolf;
Morphologic differentiation of colon carcinoma cell lines HT-29 and HT-29KM in rotating-wall vessels.
In Vitro Cell. Dev. Biol. Anim. 28:47-60(1992) |
|---|
| Cross-references |
|---|
| Cell line databases/resources |
cancercelllines; CVCL_WN77
|
|---|
| Encyclopedic resources |
Wikidata; Q94304680
|
|---|
| Entry history |
|---|
| Entry creation | 24-May-2019 |
|---|
| Last entry update | 19-Dec-2024 |
|---|
| Version number | 11 |
|---|
