| Cell line name |
NCI-H524-A |
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| Synonyms |
NCI-H524A |
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| Accession |
CVCL_WM69 |
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| Resource Identification Initiative |
To cite this cell line use: NCI-H524-A (RRID:CVCL_WM69) |
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| Comments |
Population: Caucasian.
Characteristics: Established from parent cell line by selection of the adherent cells.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029. |
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| Sequence variations |
- Mutation; HGNC; HGNC:9884; RB1; Simple; p.Ser576Ter (c.1727C>G); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Thr155Asn (c.464C>A); ClinVar=VCV000406564; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_1568 (NCI-H524) |
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| Sex of cell |
Male |
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| Age at sampling |
63Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=2473086; DOI=10.1242/jcs.91.1.91
Jos L.V. Broers, Mirjam Klein Rot, Tineke Oostendorp, Gerold Bepler, Lou F.M.H. de Leij, Desmond Niall Carney, Gijsbert Peter Vooijs, Frans C.S. Ramaekers;
Spontaneous changes in intermediate filament protein expression patterns in lung cancer cell lines.
J. Cell Sci. 91:91-108(1988) PubMed=1845952; DOI=10.1002/1097-0142(19910201)67:3<619::AID-CNCR2820670317>3.0.CO;2-Y
Jos L.V. Broers, Eddy P. Mijnheere, Mirjam Klein Rot, Gert Schaart, Alfred Sijlmans, Otto C. Boerman, Frans C.S. Ramaekers;
Novel antigens characteristic of neuroendocrine malignancies.
Cancer 67:619-633(1991) PubMed=7720728
Nicole H.M. Senden, Helgi J.K. van de Velde, Jos L.V. Broers, Erika D.J. Timmer, Helma J.H. Kuijpers, Anton J.M. Roebroek, Wim J.M. van de Ven, Frans C.S. Ramaekers;
Subcellular localization and supramolecular organization of neuroendocrine-specific protein B (NSP-B) in small cell lung cancer.
Eur. J. Cell Biol. 65:341-353(1994) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_WM69
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| Encyclopedic resources |
Wikidata; Q95993590
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| Entry history |
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| Entry creation | 24-May-2019 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 9 |
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