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Cellosaurus GG-CL (CVCL_WK94)

[Text version]
Cell line name GG-CL
Accession CVCL_WK94
Resource Identification Initiative To cite this cell line use: GG-CL (RRID:CVCL_WK94)
Comments Characteristics: Responds to stimulation by PRL, estradiol and cAMP, making the cells a useful model for studies involving gene expression and regulation of luteal cells (ABM=T0596).
Characteristics: At the permissive temperature (33 Celsius) these cells are small and compact and divide. At the non-permissive temperature (40 Celsius) the cells assume a monolayer appearance and become differentiated (PubMed=9528980).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA209).
Derived from site: In situ; Ovary, corpus luteum; UBERON=UBERON_0002512.
Cell type: Luteal cell; CL=CL_0000175.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley; RS=RS_0000681.
Hierarchy Children:
CVCL_WK95 (GG-CL PRL-R(L))
Sex of cell Female
Age at sampling Adult
Category Conditionally immortalized cell line
Publications

PubMed=9528980; DOI=10.1210/endo.139.4.5929
Sugino N., Zilberstein M., Srivastava R.K., Telleria C.M., Nelson S.E., Risk M., Chou J.Y., Gibori G.
Establishment and characterization of a simian virus 40-transformed temperature-sensitive rat luteal cell line.
Endocrinology 139:1936-1942(1998)

PubMed=9564855; DOI=10.1210/endo.139.5.5974
Telleria C.M., Zhong L.-P., Deb S., Srivastava R.K., Park K.S., Sugino N., Park-Sarge O.-K., Gibori G.
Differential expression of the estrogen receptors alpha and beta in the rat corpus luteum of pregnancy: regulation by prolactin and placental lactogens.
Endocrinology 139:2432-2442(1998)

PubMed=9675014; DOI=10.1095/biolreprod59.1.208
Sugino N., Telleria C.M., Gibori G.
Differential regulation of copper-zinc superoxide dismutase and manganese superoxide dismutase in the rat corpus luteum: induction of manganese superoxide dismutase messenger ribonucleic acid by inflammatory cytokines.
Biol. Reprod. 59:208-215(1998)

Cross-references
Cell line collections (Providers) ABM; T0596
Encyclopedic resources Wikidata; Q93560944
Entry history
Entry creation24-May-2019
Last entry update10-Apr-2025
Version number12