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Cellosaurus OCUT-2C (CVCL_W915)

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Cell line name OCUT-2C
Synonyms Ocut-2C; OCUT2C; Osaka City University Thyroid-2C
Accession CVCL_W915
Resource Identification Initiative To cite this cell line use: OCUT-2C (RRID:CVCL_W915)
Comments Population: Japanese.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23833040).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (PubMed=23833040).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Homozygous; Note=In promoter (PubMed=23833040).
Disease Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9814 (OCUT-2)
Sex of cell Female
Age at sampling 81Y
Category Cancer cell line
STR profile Source(s): CCRID=3101HUMSCSP553

Markers:
AmelogeninX
CSF1PO11
D5S81813
D7S82011
D13S31711
D16S5399
TH016,7
TPOX11
vWA14,18

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Publications

PubMed=23833040; DOI=10.1210/jc.2013-2383; PMCID=PMC3763971
Inigo Landa, Ian Ganly, Timothy A. Chan, Norisato Mitsutake, Michiko Matsuse, Tihana Ibrahimpasic, Ronald A. Ghossein, James Alexander Fagin;
Frequent somatic TERT promoter mutations in thyroid cancer: higher prevalence in advanced forms of the disease.
J. Clin. Endocrinol. Metab. 98:E1562-E1566(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W915
CCRID; 3101HUMSCSP553
Encyclopedic resources Wikidata; Q54931847
Polymorphism and mutation databases Cosmic; 2054108
Entry history
Entry creation17-Jul-2014
Last entry update19-Dec-2024
Version number17