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Cellosaurus OCUT-2 (CVCL_9814)

[Text version]
Cell line name OCUT-2
Synonyms OCUT2; Osaka City University Thyroid-2
Accession CVCL_9814
Resource Identification Initiative To cite this cell line use: OCUT-2 (RRID:CVCL_9814)
Comments Population: Japanese.
Omics: Transcriptomics; Microarray.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
Disease Thyroid gland anaplastic carcinoma (NCIt: C3878)
Anaplastic thyroid carcinoma (ORDO: Orphanet_142)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_W915 (OCUT-2C)
Sex of cell Female
Age at sampling 81Y
Category Cancer cell line
STR profile Source(s): JCRB=JCRB1870; PubMed=30737244

Markers:
AmelogeninX
CSF1PO11
D3S135815
D5S81813
D7S82011
D8S117913,14
D13S31711
D16S5399
D18S5113
D21S1130,32.2
FGA21,26
TH016,7
TPOX11
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=15785737; DOI=10.1038/sj.bjc.6602461; PMCID=PMC2361935
Yasuyuki Nobuhara, Naoyoshi Onoda, Y. Yamashita, M. Yamasaki, Kana Ogisawa, Tsutomu Takashima, Tetsuro Ishikawa, Kosei Hirakawa;
Efficacy of epidermal growth factor receptor-targeted molecular therapy in anaplastic thyroid cancer cell lines.
Br. J. Cancer 92:1110-1116(2005)

PubMed=24357248; DOI=10.1007/s00268-013-2409-7
Naoyoshi Onoda, Masanori Nakamura, Naoki Aomatsu, Satoru Noda, Shinichiro Kashiwagi, Kosei Hirakawa;
Establishment, characterization and comparison of seven authentic anaplastic thyroid cancer cell lines retaining clinical features of the original tumors.
World J. Surg. 38:688-695(2014)

PubMed=26137260; DOI=10.3892/mco.2015.496; PMCID=PMC4471583
Naoyoshi Onoda, Masanori Nakamura, Naoki Aomatsu, Satoru Noda, Shinichiro Kashiwagi, Kento Kurata, Shinya Uchino, Kosei Hirakawa;
Significant cytostatic effect of everolimus on a gefitinib-resistant anaplastic thyroid cancer cell line harboring PI3KCA gene mutation.
Mol. Clin. Oncol. 3:522-526(2015)

PubMed=30737244; DOI=10.1158/1078-0432.CCR-18-2953; PMCID=PMC6522280
Inigo Landa, Nikita Pozdeyev, Christopher T. Korch, Laura A. Marlow, Robert Christian Smallridge, John Alton Copland 3rd, Ying C. Henderson, Stephen Y. Lai, Gary L. Clayman, Naoyoshi Onoda, Aik-Choon Tan ...Show all 16 authors... , Maria E.R. Garcia-Rendueles, Jeffrey A. Knauf, Bryan R. Haugen, James Alexander Fagin, Rebecca E. Schweppe; Show fewer authors
Comprehensive genetic characterization of human thyroid cancer cell lines: a validated panel for preclinical studies.
Clin. Cancer Res. 25:3141-3151(2019)

Cross-references
Cell line collections (Providers) JCRB; JCRB1870
Cell line databases/resources cancercelllines; CVCL_9814
Anatomy/cell type resources BTO; BTO_0005143
Encyclopedic resources Wikidata; Q54931846
Polymorphism and mutation databases Cosmic; 1507373
Cosmic; 1533549
Cosmic; 1536126
Cosmic; 1889004
Cosmic; 2791082
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number20