• Gene fusion; HGNC; HGNC:3446; ERG + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ERG, EWS-ERG (PubMed=9738976).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Phe (c.527G>T); ClinVar=VCV000376569; Zygosity=Unspecified (PubMed=8221663).
  

PubMed=2486606
Yuji Fujii, Yuichi Nakagawa, Teruaki Hongo, Yoshio Igarashi, Yasuhisa Naito, Matsuyoshi Maeda;
Cell line of small round cell tumor originating in the chest wall: W-ES.
Hum. Cell 2:190-191(1989)

PubMed=2731119; DOI=10.1002/1097-0142(19890701)64:1<43::AID-CNCR2820640109>3.0.CO;2-F
Yuji Fujii, Teruaki Hongo, Yuichi Nakagawa, Kaoru Nasuda, Yoshihito Mizuno, Yoshio Igarashi, Yasuhisa Naito, Matsuyoshi Maeda;
Cell culture of small round cell tumor originating in the thoracopulmonary region. Evidence for derivation from a primitive pluripotent cell.
Cancer 64:43-51(1989)

PubMed=8221663
Hiroaki Komuro, Yasuhide Hayashi, Machiko Kawamura, Kenshi Hayashi, Yasuhiko Kaneko, Shigehiko Kamoshita, Ryoji Hanada, Keiko Yamamoto, Teruaki Hongo, Masao Yamada, Yoshiaki Tsuchida;
Mutations of the p53 gene are involved in Ewing's sarcomas but not in neuroblastomas.
Cancer Res. 53:5284-5288(1993)

PubMed=9738976; DOI=10.1111/j.1349-7006.1998.tb03274.x; PMCID=PMC5921883
Fumihiko Urano, Akihiro Umezawa, Hiroki Yabe, Wei Hong, Koichi Yoshida, Kei Fujinaga, Jun-ichi Hata;
Molecular analysis of Ewing's sarcoma: another fusion gene, EWS-E1AF, available for diagnosis.
Jpn. J. Cancer Res. 89:703-711(1998)

PubMed=12054564; DOI=10.1016/S0006-291X(02)00129-8
Hiroki Yabe, Mariko Fukuma, Fumihiko Urano, Koichi Yoshida, Shingo Kato, Yoshiaki Toyama, Jun-ichi Hata, Akihiro Umezawa;
Lack of matrix metalloproteinase (MMP)-1 and -3 expression in Ewing sarcoma may be due to loss of accessibility of the MMP regulatory element to the specific fusion protein in vivo.
Biochem. Biophys. Res. Commun. 293:61-71(2002)