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Cellosaurus HAK-2 (CVCL_W445)

[Text version]
Cell line name HAK-2
Accession CVCL_W445
Resource Identification Initiative To cite this cell line use: HAK-2 (RRID:CVCL_W445)
Comments Population: Japanese.
Doubling time: 36.8 hours (Note=At 47th passage) (PubMed=9436038).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
HLA typing Source: PubMed=9178645
Class I
HLA-AA*02:01,11:01
HLA-BB*38:01
HLA-CC*12:03
Class II
HLA-DQDQA1*01:02
DQB1*06:04
HLA-DRDRB1*13:02
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
Publications

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Seki N., Hoshino T., Kikuchi M., Hayashi A., Itoh K.
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=9178645; DOI=10.1006/cimm.1997.1108
Nakao M., Sata M., Saitsu H., Yutani S., Kawamoto M., Kojiro M., Itoh K.
CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma.
Cell. Immunol. 177:176-181(1997)

PubMed=9436038
Haramaki M., Yano H., Iemura A., Momosaki S., Ogasawara S., Inoue M., Yamaguchi R., Kusaba A., Utsunomiya I., Kojiro M.
A new human hepatocellular carcinoma cell line (HAK-2) forms various structures in collagen gel matrices.
Hum. Cell 10:183-192(1997)

PubMed=10347112; DOI=10.1002/hep.510290624
Yano H., Iemura A., Haramaki M., Ogasawara S., Takayama A., Akiba J., Kojiro M.
Interferon alfa receptor expression and growth inhibition by interferon alfa in human liver cancer cell lines.
Hepatology 29:1708-1717(1999)

Cross-references
Encyclopedic resources Wikidata; Q54872380
Entry history
Entry creation16-Apr-2014
Last entry update29-Jun-2023
Version number11