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Cellosaurus HAK-2 (CVCL_W445)

[Text version]
Cell line name HAK-2
Accession CVCL_W445
Resource Identification Initiative To cite this cell line use: HAK-2 (RRID:CVCL_W445)
Comments Population: Japanese.
Doubling time: 36.8 hours (Note=At 47th passage) (PubMed=9436038).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
HLA typing Source: PubMed=9178645
Class I
HLA-AA*02:01,11:01
HLA-BB*38:01
HLA-CC*12:03
Class II
HLA-DQDQA1*01:02
DQB1*06:04
HLA-DRDRB1*13:02
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 57Y
Category Cancer cell line
Publications

PubMed=9023415; DOI=10.1006/cimm.1996.1062
Naoko Seki, Tomoaki Hoshino, Megumi Kikuchi, Akihiro Hayashi, Kyogo Itoh;
HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.
Cell. Immunol. 175:101-110(1997)

PubMed=9178645; DOI=10.1006/cimm.1997.1108
Masanobu Nakao, Michio Sata, Hideki Saitsu, Shigeru Yutani, Mayumi Kawamoto, Masamichi Kojiro, Kyogo Itoh;
CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma.
Cell. Immunol. 177:176-181(1997)

PubMed=9436038
Makoto Haramaki, Hirohisa Yano, Akihiro Iemura, Seiya Momosaki, Sachiko Ogasawara, Michiro Inoue, Rin Yamaguchi, Akiko Kusaba, Itaru Utsunomiya, Masamichi Kojiro;
A new human hepatocellular carcinoma cell line (HAK-2) forms various structures in collagen gel matrices.
Hum. Cell 10:183-192(1997)

PubMed=10347112; DOI=10.1002/hep.510290624
Hirohisa Yano, Akihiro Iemura, Makoto Haramaki, Sachiko Ogasawara, Akiko Takayama, Jun Akiba, Masamichi Kojiro;
Interferon alfa receptor expression and growth inhibition by interferon alfa in human liver cancer cell lines.
Hepatology 29:1708-1717(1999)

Cross-references
Encyclopedic resources Wikidata; Q54872380
Entry history
Entry creation16-Apr-2014
Last entry update29-Jun-2023
Version number11