Cell line name |
Ishikawa 3-H-4 |
Accession |
CVCL_W435 |
Resource Identification Initiative |
To cite this cell line use: Ishikawa 3-H-4 (RRID:CVCL_W435) |
Comments |
Population: Japanese. Doubling time: 31.6 hours (PubMed=9183638). Derived from site: In situ; Endometrium; UBERON=UBERON_0001295. |
Sequence variations |
- Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Leu570Pro (c.1709T>C); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9177; POLE; Simple; p.Pro102Ser (c.304C>T); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9177; POLE; Simple; p.Asn751fs (c.2252delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Glu288fs*3 (c.863delA); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Thr319fs*1 (c.950_953delTACT) (p.VL317fs) (V317fs*3); Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp49His (c.145G>C); ClinVar=VCV000135948; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (from parent cell line).
|
Disease |
Type I endometrial adenocarcinoma (NCIt: C40145) |
Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
Hierarchy |
Parent: CVCL_2529 (Ishikawa) |
Sex of cell |
Female |
Age at sampling |
39Y |
Category |
Cancer cell line |
STR profile |
Source(s): PubMed=22710073
Markers:Amelogenin | X |
CSF1PO | 11,12 |
D2S1338 | 19,20 |
D3S1358 | 16,17 |
D5S818 | 10,11 |
D7S820 | 9,10 |
D8S1179 | 12,16 |
D13S317 | 9,12 |
D16S539 | 9 |
D18S51 | 13,21,22 |
D19S433 | 12.2,14 |
D21S11 | 28 |
FGA | 21,22 |
TH01 | 9,10 |
TPOX | 8 |
vWA | 14,17 |
Run an STR similarity search on this cell line |
Publications | PubMed=9183638 Masato Nishida, Kunitake Kasahara, Akinori Oki, Toyomi Satoh, Yuko Arai, Takeshi Kubo; Establishment of eighteen clones of Ishikawa cells. Hum. Cell 9:109-116(1996) DOI=10.1007/978-4-431-53981-0_2 Masato Nishida; Ishikawa cells: opening of in vitro hormone research on endometrial carcinoma. (In book chapter) Cell and molecular biology of endometrial carcinoma; Kuramoto, Hiroyuki & Nishida, Masato (eds.); pp.35-58; Springer; Tokyo; Japan (2003) PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017; PMCID=PMC3432677 Christopher T. Korch, Monique A. Spillman, Twila A. Jackson, Britta M. Jacobsen, Susan K. Murphy, Bruce Arthur Lessey, Virgil Craig Jordan, Andrew Peter Bradford; DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination. Gynecol. Oncol. 127:241-248(2012) |
Cross-references |
Cell line databases/resources |
cancercelllines; CVCL_W435
|
Encyclopedic resources |
Wikidata; Q54898300
|
Entry history |
Entry creation | 16-Apr-2014 |
Last entry update | 19-Dec-2024 |
Version number | 14 |
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