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Cellosaurus HepG2 hALR (CVCL_W371)

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Cell line name HepG2 hALR
Accession CVCL_W371
Resource Identification Initiative To cite this cell line use: HepG2 hALR (RRID:CVCL_W371)
Comments Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:4236; GFER.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0027 (Hep-G2)
Sex of cell Male
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=23797278; DOI=10.1007/s13577-013-0068-5
Hong-Ling Liu, Shao-Li You, Yi-Hui Rong, Yi-Chen Wu, Bing Zhu, Zhi-Hong Wan, Wan-Shu Liu, Pan-Yong Mao, Shao-Jie Xin;
The newly established human liver cell line: a potential cell source for the bioartificial liver in the future.
Hum. Cell 26:155-161(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W371
Encyclopedic resources Wikidata; Q54882845
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number16