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Cellosaurus SHIN-3/PTEN (CVCL_W128)

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Cell line name SHIN-3/PTEN
Accession CVCL_W128
Resource Identification Initiative To cite this cell line use: SHIN-3/PTEN (RRID:CVCL_W128)
Comments Population: Japanese.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:9588; PTEN.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Unspecified (from parent cell line).
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A670 (SHIN-3)
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=18347155; DOI=10.1158/1535-7163.MCT-06-0724
Yuji Takei, Yasushi Saga, Hiroaki Mizukami, Takeshi Takayama, Michitaka Ohwada, Keiya Ozawa, Mitsuaki Suzuki;
Overexpression of PTEN in ovarian cancer cells suppresses i.p dissemination and extends survival in mice.
Mol. Cancer Ther. 7:704-711(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_W128
Encyclopedic resources Wikidata; Q54953344
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number13