• Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (PubMed=8980248).
  
• Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Unspecified (PubMed=8980248).
  

CLPUB00115
Yasuhiko Kiyozuka, Tsuneo Noda, Masayo Maruyama, Susumu Adachi, Motohiko Ichijo, Hiroko Maeda, Junji Morimoto, Shunsuke Imai;
Establishment and characterization of CA125 and TPA producing human ovarian serous cystadenocarcinoma cell line (SHIN-3).
Hum. Cell 1:334-335(1988)

DOI=10.5795/jjscc.27.926
Yasuhiko Kiyozuka, Shunsuke Imai, Tsuneo Noda, Junji Morimoto, Ikuko Moriyama, Motohiko Ichijo, Yoshihiko Tsubura;
Establishment and characterization of human ovarian serous cystadenocarcinoma cell line (SHIN-3) which produces CA 125 and TPA in vitro.
Nihon Rinsho Saibo Gakkai Zasshi 27:926-935(1988)

PubMed=2469292; DOI=10.1111/j.1440-1827.1989.tb02401.x
Shunsuke Imai, Hiroko Maeda, Yasuhiko Kiyozuka, Tsuneo Noda, Ikuko Moriyama, Motohiko Ichijo;
Characterization of the CA125 antigen secreted from a newly established human ovarian cancer cell line (SHIN-3).
Acta Pathol. Jpn. 39:43-49(1989)

PubMed=2314830; DOI=10.1159/000226813
Shunsuke Imai, Yasuhiko Kiyozuka, Hiroko Maeda, Tsuneo Noda, Howard L. Hosick;
Establishment and characterization of a human ovarian serous cystadenocarcinoma cell line that produces the tumor markers CA-125 and tissue polypeptide antigen.
Oncology 47:177-184(1990)

PubMed=8718548
Fumihiro Murakami;
Cytotoxic action of monoclonal antibodies OC125 and SH-9 on ovarian cancer cell lines.
Nihon Sanka Fujinka Gakkai Zasshi 48:125-132(1996)

PubMed=8980248; DOI=10.1002/(SICI)1097-0215(19961220)69:6<466::AID-IJC8>3.0.CO;2-2
Yoshihito Ichikawa, Sadao Yoshida, Yumi Koyama, Misako Hirai, Tomoyoshi Ishikawa, Masato Nishida, Hajime Tsunoda, Takeshi Kubo, Masanao Miwa, Kazuhiko Uchida;
Inactivation of p16/CDKN2 and p15/MTS2 genes in different histological types and clinical stages of primary ovarian tumors.
Int. J. Cancer 69:466-470(1996)

PubMed=15677628; DOI=10.1093/carcin/bgi032
Kylie Louise Gorringe, Suet-Feung Chin, Paul D.P. Pharoah, Joanne M. Staines, Carla Oliveira, Paul A.W. Edwards, Carlos Caldas;
Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer.
Carcinogenesis 26:923-930(2005)