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Cellosaurus SGC7901/VCR (CVCL_VU58)

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Cell line name SGC7901/VCR
Accession CVCL_VU58
Resource Identification Initiative To cite this cell line use: SGC7901/VCR (RRID:CVCL_VU58)
Comments Problematic cell line: Contaminated. Parent cell line (SGC-7901) has been shown to be a HeLa derivative.
Population: African American.
Selected for resistance to: ChEBI; CHEBI_28445; Vincristine (VCR).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Proteomics; 2DE-MS.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0520 (SGC-7901)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Publications

PubMed=16038636; DOI=10.1111/j.1745-7254.2005.00149.x
Xiao-Qing Tang, Hu Bi, Jian-Qiang Feng, Jian-Guo Cao;
Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR.
Acta Pharmacol. Sin. 26:1009-1016(2005)

PubMed=16525997; DOI=10.1002/pmic.200402031
Yi-Xuan Yang, Zhi-Qiang Xiao, Zhu-Chu Chen, Gui-Ying Zhang, Hong Yi, Peng-Fei Zhang, Jian-Ling Li, Guo Zhu;
Proteome analysis of multidrug resistance in vincristine-resistant human gastric cancer cell line SGC7901/VCR.
Proteomics 6:2009-2021(2006)

PubMed=28498440; DOI=10.3892/ijo.2017.3983
Kun Zhuang, Ling-Xia Zhang, Xin Zhang, Hai-Ling Tang, Jun Zhang, Yuan Yan, Kun Han, Han-Qing Guo;
Gastrin induces multidrug resistance via the degradation of p27Kip1 in the gastric carcinoma cell line SGC7901.
Int. J. Oncol. 50:2091-2100(2017)

Cross-references
Encyclopedic resources Wikidata; Q98132472
Entry history
Entry creation24-May-2019
Last entry update10-Apr-2025
Version number7