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Cellosaurus PIG3V (CVCL_VR17)

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Cell line name PIG3V
Accession CVCL_VR17
Resource Identification Initiative To cite this cell line use: PIG3V (RRID:CVCL_VR17)
Comments Population: Caucasian.
Doubling time: 1.6 days (PubMed=10937834).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Melanocyte of skin; CL=CL_1000458.
Disease Vitiligo (NCIt: C26915)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E5FE (Ma9308)
Sex of cell Female
Age at sampling 34Y
Category Transformed cell line
Publications

PubMed=10937834; DOI=10.1290/1071-2690(2000)036<0309:PAIHVM>2.0.CO;2
Isabelle Caroline Le Poole, Raymond E. Boissy, Rangaprasad Sarangarajan, Jing Chen, Judith J. Forristal, Pranav Sheth, Wiete Westerhof, George Babcock, Pranab K. Das, Catharine B. Saelinger;
PIG3V, an immortalized human vitiligo melanocyte cell line, expresses dilated endoplasmic reticulum.
In Vitro Cell. Dev. Biol. Anim. 36:309-319(2000)

PubMed=18594937; DOI=10.1007/s11626-008-9113-1
Krassimira Ivanova, Britta Lambers, Rene M.J.G.J. van den Wijngaard, Isabelle Caroline Le Poole, Olga Grigorieva, Rupert Gerzer, Pranab K. Das;
Immortalization of human melanocytes does not alter the de novo properties of nitric oxide to induce cell detachment from extracellular matrix components via cGMP.
In Vitro Cell. Dev. Biol. Anim. 44:385-395(2008)

Cross-references
Encyclopedic resources Wikidata; Q98128589
Entry history
Entry creation13-Nov-2018
Last entry update14-Aug-2025
Version number11