ID   PIG3V
AC   CVCL_VR17
DR   Wikidata; Q98128589
RX   PubMed=10937834;
RX   PubMed=18594937;
CC   Population: Caucasian.
CC   Doubling time: 1.6 days (PubMed=10937834).
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
CC   Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
CC   Derived from site: In situ; Skin; UBERON=UBERON_0002097.
CC   Cell type: Melanocyte of skin; CL=CL_1000458.
DI   NCIt; C26915; Vitiligo
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_E5FE ! Ma9308
SX   Female
AG   34Y
CA   Transformed cell line
DT   Created: 13-11-18; Last updated: 10-04-25; Version: 10
//
RX   PubMed=10937834; DOI=10.1290/1071-2690(2000)036<0309:PAIHVM>2.0.CO;2;
RA   Le Poole I.C., Boissy R.E., Sarangarajan R., Chen J., Forristal J.J.,
RA   Sheth P., Westerhof W., Babcock G., Das P.K., Saelinger C.B.;
RT   "PIG3V, an immortalized human vitiligo melanocyte cell line, expresses
RT   dilated endoplasmic reticulum.";
RL   In Vitro Cell. Dev. Biol. Anim. 36:309-319(2000).
//
RX   PubMed=18594937; DOI=10.1007/s11626-008-9113-1;
RA   Ivanova K., Lambers B., van den Wijngaard R.M.J.G.J., Le Poole I.C.,
RA   Grigorieva O., Gerzer R., Das P.K.;
RT   "Immortalization of human melanocytes does not alter the de novo
RT   properties of nitric oxide to induce cell detachment from
RT   extracellular matrix components via cGMP.";
RL   In Vitro Cell. Dev. Biol. Anim. 44:385-395(2008).
//