Cellosaurus Pten+/- Ctnnb1 ex3del CP1 (CVCL_VQ84)
| Cell line name | Pten+/- Ctnnb1 ex3del CP1 |
|---|---|
| Synonyms | CP1 |
| Accession | CVCL_VQ84 |
| Resource Identification Initiative | To cite this cell line use: Pten+/- Ctnnb1 ex3del CP1 (RRID:CVCL_VQ84) |
| Comments | Characteristics: Prostate cell line with Ctnnb1 gain of function mutation. Established from a mouse prostate epithelium tumor in a mouse with probasin Cre driven exon 3 deletion of one Ctnnb1 allele and a Pten heterozygous deletion. Characteristics: Tumorigenic in immunocompromised mice (CD-1 nudes) and in immunocompetent mice (C57BL/6J- WT colony controls) as prostate orthografts. Doubling time: ~13 hours (Note=In DMEM with glutamine + 10% FBS) (Direct_author_submission). Knockout cell: Method=KO mouse; MGI; MGI:109583; Pten. Miscellaneous: Cell line information from personal communication of Patel, Rachana. Derived from site: In situ; Prostate; UBERON=UBERON_0002367. |
| Disease | Carcinoma of the mouse prostate gland (NCIt: C21732) |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6J Ctnnb1pc(ex3)delta/+ Ptenpcfl/+. |
| Sex of cell | Male |
| Age at sampling | 6M |
| Category | Cancer cell line |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q98128697 |
| Entry history | |
| Entry creation | 13-Nov-2018 |
| Last entry update | 10-Sep-2024 |
| Version number | 7 |