ID   Pten+/- Ctnnb1 ex3del CP1
AC   CVCL_VQ84
SY   CP1
DR   Wikidata; Q98128697
CC   Characteristics: Prostate cell line with Ctnnb1 gain of function mutation. Established from a mouse prostate epithelium tumor in a mouse with probasin Cre driven exon 3 deletion of one Ctnnb1 allele and a Pten heterozygous deletion.
CC   Characteristics: Tumorigenic in immunocompromised mice (CD-1 nudes) and in immunocompetent mice (C57BL/6J- WT colony controls) as prostate orthografts.
CC   Doubling time: ~13 hours (Note=In DMEM with glutamine + 10% FBS) (Direct_author_submission).
CC   Knockout cell: Method=KO mouse; MGI; MGI:109583; Pten.
CC   Miscellaneous: Cell line information from personal communication of Patel, Rachana.
CC   Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
CC   Breed/subspecies: C57BL/6J Ctnnb1pc(ex3)delta/+ Ptenpcfl/+.
DI   NCIt; C21732; Carcinoma of the mouse prostate gland
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Male
AG   6M
CA   Cancer cell line
DT   Created: 13-11-18; Last updated: 10-09-24; Version: 7
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