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Cellosaurus ATL-55T (CVCL_VQ17)

[Text version]
Cell line name ATL-55T
Synonyms ATL-55T(+)
Accession CVCL_VQ17
Resource Identification Initiative To cite this cell line use: ATL-55T (RRID:CVCL_VQ17)
Comments Population: Japanese.
Characteristics: IL2 dependent.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Disease Adult T-cell leukemia/lymphoma (NCIt: C3184)
Adult T-cell leukemia/lymphoma (ORDO: Orphanet_86875)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A6SG (ATL-55T(-))
Sex of cell Sex unspecified
Age at sampling Adult
Category Cancer cell line

PubMed=2889484; DOI=10.1182/blood.V70.5.1407.1407
Maeda M., Arima N., Daitoku Y., Kashihara M., Okamoto H., Uchiyama T., Shirono K., Matsuoka M., Hattori T., Takatsuki K., Ikuta K., Shimizu A., Honjo T., Yodoi J.
Evidence for the interleukin-2 dependent expansion of leukemic cells in adult T cell leukemia.
Blood 70:1407-1411(1987)

Nosaka K., Maeda M., Tamiya S., Sakai T., Mitsuya H., Matsuoka M.
Increasing methylation of the CDKN2A gene is associated with the progression of adult T-cell leukemia.
Cancer Res. 60:1043-1048(2000)

PubMed=16242045; DOI=10.1186/1742-4690-2-64
Taniguchi Y., Nosaka K., Yasunaga J.-i., Maeda M., Mueller N., Okayama A., Matsuoka M.
Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms.
Retrovirology 2:64.1-64.16(2005)

PubMed=32210945; DOI=10.3389/fmicb.2020.00356
Maeda M., Tanabe-Shibuya J., Miyazato P., Masutani H., Yasunaga J.-i., Usami K., Shimizu A., Matsuoka M.
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

Cell line collections (Providers) RCB; RCB3537
Encyclopedic resources Wikidata; Q93326751
Entry history
Entry creation07-Sep-2018
Last entry update29-Jun-2023
Version number9