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Cellosaurus ATL-55T (CVCL_VQ17)

[Text version]
Cell line name ATL-55T
Synonyms ATL-55T(+)
Accession CVCL_VQ17
Resource Identification Initiative To cite this cell line use: ATL-55T (RRID:CVCL_VQ17)
Comments Population: Japanese.
Characteristics: IL2 dependent.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Disease Adult T-cell leukemia/lymphoma (NCIt: C3184)
Adult T-cell leukemia/lymphoma (ORDO: Orphanet_86875)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A6SG (ATL-55T(-))
Sex of cell Sex unspecified
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=2889484; DOI=10.1182/blood.V70.5.1407.1407
Michiyuki Maeda, Naomichi Arima, Yasuhisa Daitoku, Mari Kashihara, Hiroyuki Okamoto, Takashi Uchiyama, Kenji Shirono, Masao Matsuoka, Toshio Hattori, Kiyoshi Takatsuki, Koichi Ikuta ...Show all 14 authors... , Akira Shimizu, Tasuku Honjo, Junji Yodoi; Show fewer authors
Evidence for the interleukin-2 dependent expansion of leukemic cells in adult T cell leukemia.
Blood 70:1407-1411(1987)

PubMed=10706122
Kisato Nosaka, Michiyuki Maeda, Sadahiro Tamiya, Tatsunori Sakai, Hiroaki Mitsuya, Masao Matsuoka;
Increasing methylation of the CDKN2A gene is associated with the progression of adult T-cell leukemia.
Cancer Res. 60:1043-1048(2000)

PubMed=16242045; DOI=10.1186/1742-4690-2-64; PMCID=PMC1289293
Yuko Taniguchi, Kisato Nosaka, Jun-ichirou Yasunaga, Michiyuki Maeda, Nancy Mueller, Akihiko Okayama, Masao Matsuoka;
Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms.
Retrovirology 2:64.1-64.16(2005)

PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701
Michiyuki Maeda, Junko Tanabe-Shibuya, Paola Miyazato, Hiroshi Masutani, Jun-ichirou Yasunaga, Kazumasa Usami, Akira Shimizu, Masao Matsuoka;
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

Cross-references
Cell line collections (Providers) RCB; RCB3537
Encyclopedic resources Wikidata; Q93326751
Entry history
Entry creation07-Sep-2018
Last entry update29-Jun-2023
Version number9