ID   ATL-55T
AC   CVCL_VQ17
SY   ATL-55T(+)
DR   RCB; RCB3537
DR   Wikidata; Q93326751
RX   PubMed=2889484;
RX   PubMed=10706122;
RX   PubMed=16242045;
RX   PubMed=32210945;
CC   Population: Japanese.
CC   Characteristics: IL2 dependent.
CC   Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
CC   Cell type: T-cell; CL=CL_0000084.
DI   NCIt; C3184; Adult T-cell leukemia/lymphoma
DI   ORDO; Orphanet_86875; Adult T-cell leukemia/lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Sex unspecified
AG   Adult
CA   Cancer cell line
DT   Created: 07-09-18; Last updated: 29-06-23; Version: 9
CH   CVCL_A6SG ! ATL-55T(-)
//
RX   PubMed=2889484; DOI=10.1182/blood.V70.5.1407.1407;
RA   Maeda, Michiyuki
RA   Arima, Naomichi
RA   Daitoku, Yasuhisa
RA   Kashihara, Mari
RA   Okamoto, Hiroyuki
RA   Uchiyama, Takashi
RA   Shirono, Kenji
RA   Matsuoka, Masao
RA   Hattori, Toshio
RA   Takatsuki, Kiyoshi
RA   Ikuta, Koichi
RA   Shimizu, Akira
RA   Honjo, Tasuku
RA   Yodoi, Junji
RT   "Evidence for the interleukin-2 dependent expansion of leukemic cells
RT   in adult T cell leukemia.";
RL   Blood 70:1407-1411(1987).
//
RX   PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701;
RA   Maeda, Michiyuki
RA   Tanabe-Shibuya, Junko
RA   Miyazato, Paola
RA   Masutani, Hiroshi
RA   Yasunaga, Jun-ichirou
RA   Usami, Kazumasa
RA   Shimizu, Akira
RA   Matsuoka, Masao
RT   "IL-2/IL-2 receptor pathway plays a crucial role in the growth and
RT   malignant transformation of HTLV-1-infected T cells to develop adult
RT   T-cell leukemia.";
RL   Front. Microbiol. 11:356.1-356.17(2020).
//
RX   PubMed=10706122;
RA   Nosaka, Kisato
RA   Maeda, Michiyuki
RA   Tamiya, Sadahiro
RA   Sakai, Tatsunori
RA   Mitsuya, Hiroaki
RA   Matsuoka, Masao
RT   "Increasing methylation of the CDKN2A gene is associated with the
RT   progression of adult T-cell leukemia.";
RL   Cancer Res. 60:1043-1048(2000).
//
RX   PubMed=16242045; DOI=10.1186/1742-4690-2-64; PMCID=PMC1289293;
RA   Taniguchi, Yuko
RA   Nosaka, Kisato
RA   Yasunaga, Jun-ichirou
RA   Maeda, Michiyuki
RA   Mueller, Nancy
RA   Okayama, Akihiko
RA   Matsuoka, Masao
RT   "Silencing of human T-cell leukemia virus type I gene transcription by
RT   epigenetic mechanisms.";
RL   Retrovirology 2:64.1-64.16(2005).
//