Cellosaurus cell line ATL-21C (CVCL_VQ15)

Cellosaurus ATL-21C (CVCL_VQ15)

Cell line name

ATL-21C

Synonyms

ATL-21C(+)

Accession

CVCL_VQ15

Resource Identification Initiative

To cite this cell line use: ATL-21C (RRID:CVCL_VQ15)

Comments

Population: Japanese.
Characteristics: IL2 dependent.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Donor information: Established from a patient suffering from adult T-cell leukemia/lymphoma (ATLL).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_A6TI (ATL-21C(-)/2)

CVCL_A6TQ (ATL-21C(-)/3.8)

CVCL_A6TP (ATL-21C(-)/8.9)

Sex of cell

Sex unspecified

Age at sampling

Adult

Category

Transformed cell line

Publications

PubMed=16242045; DOI=10.1186/1742-4690-2-64; PMCID=PMC1289293
Yuko Taniguchi, Kisato Nosaka, Jun-ichirou Yasunaga, Michiyuki Maeda, Nancy Mueller, Akihiko Okayama, Masao Matsuoka;
Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms.
Retrovirology 2:64.1-64.16(2005)

PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701
Michiyuki Maeda, Junko Tanabe-Shibuya, Paola Miyazato, Hiroshi Masutani, Jun-ichirou Yasunaga, Kazumasa Usami, Akira Shimizu, Masao Matsuoka;
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

Cross-references

Cell line collections (Providers)

RCB; RCB3551

Encyclopedic resources

Wikidata; Q93326733

Entry history

Entry creation

07-Sep-2018

Last entry update

29-Jun-2023

Version number

9