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Cellosaurus ATL-21C (CVCL_VQ15)

[Text version]
Cell line name ATL-21C
Synonyms ATL-21C(+)
Accession CVCL_VQ15
Resource Identification Initiative To cite this cell line use: ATL-21C (RRID:CVCL_VQ15)
Comments Population: Japanese.
Characteristics: IL2 dependent.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Donor information: Established from a patient suffering from adult T-cell leukemia/lymphoma (ATLL).
Derived from sampling site: Peripheral blood. Cell type=T-cell.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A6TI (ATL-21C(-)/2)CVCL_A6TQ (ATL-21C(-)/3.8)CVCL_A6TP (ATL-21C(-)/8.9)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=16242045; DOI=10.1186/1742-4690-2-64
Taniguchi Y., Nosaka K., Yasunaga J.-I., Maeda M., Mueller N., Okayama A., Matsuoka M.
Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms.
Retrovirology 2:64.1-64.16(2005)

PubMed=32210945; DOI=10.3389/fmicb.2020.00356
Maeda M., Tanabe-Shibuya J., Miyazato P., Masutani H., Yasunaga J.-I., Usami K., Shimizu A., Matsuoka M.
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

Cross-references
Cell line collections RCB; RCB3551
Encyclopedic resources Wikidata; Q93326733
Entry history
Entry creation07-Sep-2018
Last entry update21-Mar-2023
Version number8