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Cellosaurus ATL-21C(-)/8.9 (CVCL_A6TP)

[Text version]
Cell line name ATL-21C(-)/8.9
Accession CVCL_A6TP
Resource Identification Initiative To cite this cell line use: ATL-21C(-)/8.9 (RRID:CVCL_A6TP)
Comments Population: Japanese.
Characteristics: Lost its original IL2 dependency. Cultured for 8.9 years without IL2.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Donor information: Established from a patient suffering from adult T-cell leukemia/lymphoma (ATLL).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_VQ15 (ATL-21C)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=32210945; DOI=10.3389/fmicb.2020.00356; PMCID=PMC7067701
Michiyuki Maeda, Junko Tanabe-Shibuya, Paola Miyazato, Hiroshi Masutani, Jun-ichirou Yasunaga, Kazumasa Usami, Akira Shimizu, Masao Matsuoka;
IL-2/IL-2 receptor pathway plays a crucial role in the growth and malignant transformation of HTLV-1-infected T cells to develop adult T-cell leukemia.
Front. Microbiol. 11:356.1-356.17(2020)

Cross-references
Cell line collections (Providers) RCB; RCB3553
Encyclopedic resources Wikidata; Q107113394
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number7