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Cellosaurus MBT-2V (CVCL_VL61)

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Cell line name MBT-2V
Synonyms MBT-2 variant
Accession CVCL_VL61
Resource Identification Initiative To cite this cell line use: MBT-2V (RRID:CVCL_VL61)
Comments Characteristics: High metastatic potential. Established from a lung metastasis nodule in C3H mice implanted with the parent cell line in the leg muscles (PubMed=16140114).
Transformant: ChEBI; CHEBI_82328; Nifurthiazole (N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide; FANFT).
Derived from site: Metastatic; Urinary bladder; UBERON=UBERON_0001255.
Disease Mouse bladder transitional cell carcinoma (NCIt: C25823)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/He.
Hierarchy Parent: CVCL_4660 (MBT-2)
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=16140114; DOI=10.1016/j.urology.2005.03.073
Minoru Horinaga, Ryuichi Fukuyama, Toru Nishiyama, Kelley M. Harsch, Muzaffer Cicek, Warren D.W. Heston, Nywana Sizemore, Graham Casey, William Aram Larchian;
Novel enhanced lung-colonizing variant of murine MBT-2 bladder cancer cells.
Urology 66:676-681(2005)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus Christiaan de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Encyclopedic resources Wikidata; Q95985633
Entry history
Entry creation07-Sep-2018
Last entry update14-Aug-2025
Version number7