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Cellosaurus MBT-2 (CVCL_4660)

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Cell line name MBT-2
Synonyms MBT2; Mouse Bladder Tumor line-2
Accession CVCL_4660
Resource Identification Initiative To cite this cell line use: MBT-2 (RRID:CVCL_4660)
Comments Transformant: ChEBI; CHEBI_82328; Nifurthiazole (N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide; FANFT).
Derived from site: Metastatic; Urinary bladder; UBERON=UBERON_0001255.
Disease Mouse bladder transitional cell carcinoma (NCIt: C25823)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/He.
Hierarchy Children:
CVCL_E3KQ (HyCyte MBT-2-Luc)CVCL_VL61 (MBT-2V)
Sex of cell Female
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=406041
Mark Stephen Soloway;
Intravesical and systemic chemotherapy of murine bladder cancer.
Cancer Res. 37:2918-2929(1977)

PubMed=16140114; DOI=10.1016/j.urology.2005.03.073
Minoru Horinaga, Ryuichi Fukuyama, Toru Nishiyama, Kelley M. Harsch, Muzaffer Cicek, Warren D.W. Heston, Nywana Sizemore, Graham Casey, William Aram Larchian;
Novel enhanced lung-colonizing variant of murine MBT-2 bladder cancer cells.
Urology 66:676-681(2005)

DOI=10.4051/ibc.2010.2.4.0014
Kaori Yoshino, Kaoru Saijo, Chikako Noro, Yukio Nakamura;
Development of a simple method to determine the mouse strain from which cultured cell lines originated.
Interdisciplinary Bio Cent. 2:14.1-14.9(2010)

PubMed=29732388; DOI=10.3233/BLC-180167; PMCID=PMC5929350
Tahlita C.M. Zuiverloon, Florus Christiaan de Jong, James C. Costello, Dan Theodorescu;
Systematic review: characteristics and preclinical uses of bladder cancer cell lines.
Bladder Cancer 4:169-183(2018)

Cross-references
Cell line collections (Providers) JCRB; IFO50041
RCB; RCB0544
Cell line databases/resources CLO; CLO_0050945
Anatomy/cell type resources BTO; BTO_0003555
Encyclopedic resources Wikidata; Q54904157
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number15