Cellosaurus logo
expasy logo

Cellosaurus TSCCa (CVCL_VL15)

[Text][XML][JSON]
Cell line name TSCCa
Synonyms TSCCA
Accession CVCL_VL15
Resource Identification Initiative To cite this cell line use: TSCCa (RRID:CVCL_VL15)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706; PubMed=28107433). Originally thought to originate from a tongue squamous cell carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00579.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=26116706; PubMed=28107433

Markers:
AmelogeninX
CSF1PO9,10
D2S44110,11
D2S133817
D3S135815,18
D5S81811,12
D7S8208,12
D8S117912,13
D12S39120,25
D13S31712,13.3
D16S5399,10
D18S5116
D19S43313,14
D21S1127,28
FGA21
Penta D8,13 (PubMed=28107433)
8,15 (PubMed=26116706)
Penta E7,17
TH017
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=10779629; DOI=10.1016/S0304-3835(00)00389-X
Yean-Jang Lee, Pel-Hu Liao, Wen-Kang Chen, Chi-Chiang Yang;
Preferential cytotoxicity of caffeic acid phenethyl ester analogues on oral cancer cells.
Cancer Lett. 153:51-56(2000)

PubMed=12149736; DOI=10.1053/joms.2002.33860
Zheng-Jun Shang, Jin-Rong Li, Zu-Bing Li;
Effects of exogenous nitric oxide on oral squamous cell carcinoma: an in vitro study.
J. Oral Maxillofac. Surg. 60:905-910(2002)

PubMed=15929393
Chi-Ruei Huang, Shih-Shen Lin, Ming-Yung Chou, Chuan-Chen Ho, Li-Na Wang, Yin-Lau Lee, Chung-Shih Chen, Chi-Chiang Yang;
Demonstration of different modes of cell death upon herpes simplex virus 1 infection in different types of oral cells.
Acta Virol. 49:7-15(2005)

PubMed=26116706; DOI=10.1096/fj.14-266718
Fang Ye, Chu-Guang Chen, Jian Qin, Jie Liu, Cong-Yi Zheng;
Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China.
FASEB J. 29:4268-4272(2015)

PubMed=28107433; DOI=10.1371/journal.pone.0170384; PMCID=PMC5249119
Ya-Qing Huang, Yue-Hong Liu, Cong-Yi Zheng, Chao Shen;
Investigation of cross-contamination and misidentification of 278 widely used tumor cell lines.
PLoS ONE 12:e0170384.1-e0170384.16(2017)

Cross-references
Cell line collections (Providers) CCTCC; GDC0184
Anatomy/cell type resources BTO; BTO_0006082
Encyclopedic resources Wikidata; Q98133629
Entry history
Entry creation07-Sep-2018
Last entry update10-Apr-2025
Version number12