Cellosaurus cell line F2N78 (CVCL

Cellosaurus F2N78 (CVCL_VK71)

Cross-references
Cell line name	F2N78
Synonyms	F2N clone 78; Fusion of 293 cells with Namalwa, clone 78
Accession	CVCL_VK71
Resource Identification Initiative	To cite this cell line use: F2N78 (RRID:CVCL_VK71)
Comments	Characteristics: Developed for recombinant proteins production. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0045 (HEK293) Parent: CVCL_0067 (Namalwa)
Category	Hybrid cell line
Publications	PubMed=23296943; DOI=10.1002/btpr.1685 Hyun-Joo Lee, MinSeok Chang, Jong-Mook Kim, HyeJin Hong, Ki Eun Maeng, Jane Koo, Shin-Jae Chang, Myung-Sam Cho; Application of a new human cell line, F2N78, in the transient and stable production of recombinant therapeutics. Biotechnol. Prog. 29:432-440(2013) PubMed=26454770; DOI=10.1016/j.jbiosc.2015.07.007 Joon Serk Seo, Byung Sub Min, Young-Bum Kwon, Soo-Young Lee, Jong-Moon Cho, Keun-Hee Park, Yae Ji Yang, Ki Eun Maeng, Shin-Jae Chang, Dong-Il Kim; Characteristics of human cell line, F2N78, for the production of recombinant antibody in fed-batch and perfusion cultures. J. Biosci. Bioeng. 121:317-324(2016) PubMed=28054185; DOI=10.1007/s10529-016-2281-2 Joon Serk Seo, Byung Sub Min, Yeon Jung Kim, Jong Moon Cho, Gi-Seong Kwon, Byeong-Pil Lim, Shin-Jae Chang, Dong-Il Kim; Characterization of human hybrid cell line, F2N78, through a comparison of culture performances and protein qualities. Biotechnol. Lett. 39:501-509(2017)
Encyclopedic resources	Wikidata; Q93548602
Entry history
Entry creation	07-Sep-2018
Last entry update	14-Aug-2025
Version number	5