ID   F2N78
AC   CVCL_VK71
SY   F2N clone 78; Fusion of 293 cells with Namalwa, clone 78
DR   Wikidata; Q93548602
RX   PubMed=23296943;
RX   PubMed=26454770;
RX   PubMed=28054185;
CC   Characteristics: Developed for recombinant proteins production.
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 28285; Adenovirus 5.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0045 ! HEK293
HI   CVCL_0067 ! Namalwa
CA   Hybrid cell line
DT   Created: 07-09-18; Last updated: 21-03-23; Version: 3
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RX   PubMed=23296943; DOI=10.1002/btpr.1685;
RA   Lee H.-J., Chang M., Kim J.-M., Hong H., Maeng K.E., Koo J.,
RA   Chang S.-J., Cho M.-S.;
RT   "Application of a new human cell line, F2N78, in the transient and
RT   stable production of recombinant therapeutics.";
RL   Biotechnol. Prog. 29:432-440(2013).
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RX   PubMed=26454770; DOI=10.1016/j.jbiosc.2015.07.007;
RA   Seo J.S., Min B.S., Kwon Y.-B., Lee S.-Y., Cho J.-M., Park K.-H.,
RA   Yang Y.J., Maeng K.E., Chang S.-J., Kim D.-I.;
RT   "Characteristics of human cell line, F2N78, for the production of
RT   recombinant antibody in fed-batch and perfusion cultures.";
RL   J. Biosci. Bioeng. 121:317-324(2016).
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RX   PubMed=28054185; DOI=10.1007/s10529-016-2281-2;
RA   Seo J.S., Min B.S., Kim Y.J., Cho J.M., Kwon G.-S., Lim B.-P.,
RA   Chang S.-J., Kim D.-I.;
RT   "Characterization of human hybrid cell line, F2N78, through a
RT   comparison of culture performances and protein qualities.";
RL   Biotechnol. Lett. 39:501-509(2017).
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