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Cellosaurus VACO 8-2 (CVCL_VK10)

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Cell line name VACO 8-2
Synonyms Vaco 8-2; VACO8-2; Vaco8-2
Accession CVCL_VK10
Resource Identification Initiative To cite this cell line use: VACO 8-2 (RRID:CVCL_VK10)
Comments Microsatellite instability: Stable (MSS) (PubMed=9927040).
Derived from site: In situ; Cecum; UBERON=UBERON_0001153.
Sequence variations
  • Mutation; HGNC; HGNC:11773; TGFBR2; Simple; p.Asp522Asn (c.1564G>A); ClinVar=VCV000213936; Zygosity=Homozygous (PubMed=9927040).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro190Leu (c.569C>T); ClinVar=VCV000418517; Zygosity=Hemizygous (from parent cell line).
Disease Cecum adenocarcinoma (NCIt: C5543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5411 (VACO 8)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=9927040
William M. Grady, Lois Lemmermann Myeroff, Sandra E. Swinler, Ashwani Rajput, Sam Thiagalingam, James D. Lutterbaugh, Aaron Neumann, Michael G. Brattain, Jay Chang, Seong-Jin Kim, Kenneth Wayne Kinzler ...Show all 14 authors... , Bert Vogelstein, James K.V. Willson, Sanford David Markowitz; Show fewer authors
Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers.
Cancer Res. 59:320-324(1999)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VK10
Encyclopedic resources Wikidata; Q98134469
Polymorphism and mutation databases Cosmic; 2647360
Entry history
Entry creation07-Sep-2018
Last entry update19-Dec-2024
Version number9