• Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro190Leu (c.569C>T); ClinVar=VCV000418517; Zygosity=Hemizygous (PubMed=9715273).
  

PubMed=6498841
John A. McBain, James L. Weese, Lorraine Faxon Meisner, William H. Wolberg, James K.V. Willson;
Establishment and characterization of human colorectal cancer cell lines.
Cancer Res. 44:5813-5821(1984)

PubMed=8385345; DOI=10.1073/pnas.90.7.2846; PMCID=PMC46193
Kelly J. Smith, Karen Audrey Johnson, Tracy M. Bryan, David E. Hill, Sanford David Markowitz, James K.V. Willson, Christos Paraskeva, Gloria Moy Petersen, Stanley R. Hamilton, Bert Vogelstein, Kenneth Wayne Kinzler;
The APC gene product in normal and tumor cells.
Proc. Natl. Acad. Sci. U.S.A. 90:2846-2850(1993)

PubMed=7761852; DOI=10.1126/science.7761852
Sanford David Markowitz, Jing Wang, Lois Lemmermann Myeroff, Ramon Parsons, Lu-Zhe Sun, James D. Lutterbaugh, Robert S. Fan, Elizabeth Zborowska, Kenneth Wayne Kinzler, Bert Vogelstein, Michael G. Brattain, James K.V. Willson;
Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability.
Science 268:1336-1338(1995)

PubMed=8755562; DOI=10.1073/pnas.93.15.7832; PMCID=PMC38834
Da-Cai Liu, Eric Pearlman, Eugenia Diaconu, Kun Guo, Hiroshi Mori, Tariq Haqqi, Sanford David Markowitz, James K.V. Willson, Man-Sun Sy;
Expression of hyaluronidase by tumor cells induces angiogenesis in vivo.
Proc. Natl. Acad. Sci. U.S.A. 93:7832-7837(1996)

PubMed=9715273; DOI=10.1038/sj.onc.1201986
James Richard Eshleman, Graham Casey, Mary E. Kochera, Wallace David Sedwick, Sandra E. Swinler, Martina L. Veigl, James K.V. Willson, Stuart Schwartz, Sanford David Markowitz;
Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53.
Oncogene 17:719-725(1998)

PubMed=11314036; DOI=10.1038/sj.onc.1204211
Eva Forgacs, Jonathan D. Wren, Craig Kamibayashi, Masashi Kondo, Xie L. Xu, Sanford David Markowitz, Gail E. Tomlinson, Carolyn Y. Muller, Adi F. Gazdar, Harold Ray Garner, John D. Minna;
Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.
Oncogene 20:1005-1009(2001)