Cellosaurus logo
expasy logo

Cellosaurus ORL-195 (CVCL_VJ43)

[Text version]
Cell line name ORL-195
Synonyms ORL-195T; 195T
Accession CVCL_VJ43
Resource Identification Initiative To cite this cell line use: ORL-195 (RRID:CVCL_VJ43)
Comments Population: Indian.
Omics: Phenotyping; CRISPR screening.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Oral cavity, buccal mucosa; UBERON=UBERON_0006956.
Sequence variations
Disease Buccal mucosa squamous cell carcinoma (NCIt: C4040)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 61Y
Category Cancer cell line
STR profile Source(s): PubMed=27050151

Markers:
AmelogeninX
CSF1PO11,12
D2S133819
D3S135817
D5S81811,16
D7S82010,11
D8S117914,16
D13S31711,12
D16S53911,12
D18S5113
D19S43313,15.2
D21S1129,31.2
FGA24
TH016,9
TPOX8,9
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=24224046; DOI=10.1371/journal.pone.0080229; PMCID=PMC3817115
Sharifah Nurain Syed Zanaruddin, Pei-San Yee, Seen Yii Hor, Yink Heay Kong, Wan Maria Nabillah Wan Abd Ghani, Wan Mahadzir Wan Mustafa, Rosnah Binti Zain, Stephen S. Prime, Zainal Ariff Abdul Rahman, Sok-Ching Cheong;
Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin.
PLoS ONE 8:e80229.1-e80229.12(2013)

PubMed=27050151; DOI=10.18632/oncotarget.8533; PMCID=PMC5053689
Muhammad Zaki Hidayatullah Fadlullah, Ivy Kim-Ni Chiang, Kalen R. Dionne, Pei-San Yee, Chai Phei Gan, Kin Kit Sam, Kai Hung Tiong, Adrian Kwok Wen Ng, Daniel Martin, Kue Peng Lim, Thomas George Kallarakkal ...Show all 21 authors... , Wan Mahadzir Wan Mustafa, Shin Hin Lau, Mannil Thomas Abraham, Rosnah Binti Zain, Zainal Ariff Abdul Rahman, Alfredo Alberto Molinolo, Vyomesh Patel, J. Silvio Gutkind, Aik-Choon Tan, Sok-Ching Cheong; Show fewer authors
Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies.
Oncotarget 7:27802-27818(2016)

PubMed=32990596; DOI=10.7554/eLife.57761; PMCID=PMC7591259
Annie Wai-Yeeng Chai, Pei-San Yee, Stacey Price, Shi-Mun Yee, Hui-Mei Lee, Vivian K.H. Tiong, Emanuel Goncalves, Fiona M. Behan, Jessica Bateson, James G.R. Gilbert, Aik-Choon Tan ...Show all 14 authors... , Ultan McDermott, Mathew J. Garnett, Sok-Ching Cheong; Show fewer authors
Genome-wide CRISPR screens of oral squamous cell carcinoma reveal fitness genes in the Hippo pathway.
eLife 9:e57761.1-e57761.34(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VJ43
Cell_Model_Passport; SIDM01999
CRISP screens repositories BioGRID_ORCS_Cell_line; 1277
Encyclopedic resources Wikidata; Q98128363
Polymorphism and mutation databases Cosmic; 2531647
Cosmic; 2559743
Entry history
Entry creation07-Sep-2018
Last entry update10-Apr-2025
Version number12