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Cellosaurus BJAB GFP-MS4A7 (CVCL_VD95)

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Cell line name BJAB GFP-MS4A7
Accession CVCL_VD95
Resource Identification Initiative To cite this cell line use: BJAB GFP-MS4A7 (RRID:CVCL_VD95)
Comments Population: African; Kenyan.
Characteristics: Expresses GFP fused to the N-terminus of MS4A7/CD20L4 (PubMed=23874341).
Virology: EBV-negative.
Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:13378; MS4A7.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5711 (BJAB)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=23874341; DOI=10.3389/fimmu.2013.00195; PMCID=PMC3711070
Jonathan Zuccolo, Li-Li Deng, Tammy L. Unruh, Ratna Sanyal, Jeremy A. Bau, Jan Storek, Douglas J. Demetrick, Joanne M. Luider, Iwona A. Auer-Grzesiak, Adnan Mansoor, Julie P. Deans;
Expression of MS4A and TMEM176 genes in human B lymphocytes.
Front. Immunol. 4:195.1-195.7(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_VD95
Encyclopedic resources Wikidata; Q54796983
Entry history
Entry creation14-May-2018
Last entry update14-Aug-2025
Version number14