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Cellosaurus BJAB GFP-CD20 (CVCL_VD92)

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Cell line name BJAB GFP-CD20
Accession CVCL_VD92
Resource Identification Initiative To cite this cell line use: BJAB GFP-CD20 (RRID:CVCL_VD92)
Comments Population: African; Kenyan.
Characteristics: Expresses GFP fused to the N-terminus of MS4A1/CD20.
Virology: EBV-negative.
Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:7315; MS4A1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Derived from site: In situ; Groin; UBERON=UBERON_0008337.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.His193Arg (c.578A>G); ClinVar=VCV000184979; Zygosity=Unspecified (from parent cell line).
Disease Burkitt lymphoma (NCIt: C2912)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5711 (BJAB)
Sex of cell Female
Age at sampling 5Y
Category Cancer cell line
Publications

PubMed=14976189; DOI=10.1074/jbc.M400525200
Hai-Dong Li, Linda M. Ayer, Maria J. Polyak, Cathlin M. Mutch, Ryan J. Petrie, Laura Gauthier, Neda Shariat, Michael J. Hendzel, Andrew R.E. Shaw, Kamala D. Patel, Julie P. Deans;
The CD20 calcium channel is localized to microvilli and constitutively associated with membrane rafts: antibody binding increases the affinity of the association through an epitope-dependent cross-linking-independent mechanism.
J. Biol. Chem. 279:19893-19901(2004)

PubMed=23874341; DOI=10.3389/fimmu.2013.00195; PMCID=PMC3711070
Jonathan Zuccolo, Li-Li Deng, Tammy L. Unruh, Ratna Sanyal, Jeremy A. Bau, Jan Storek, Douglas J. Demetrick, Joanne M. Luider, Iwona A. Auer-Grzesiak, Adnan Mansoor, Julie P. Deans;
Expression of MS4A and TMEM176 genes in human B lymphocytes.
Front. Immunol. 4:195.1-195.7(2013)

Cross-references
Cell line collections (Providers) Kerafast; EUC018
Cell line databases/resources cancercelllines; CVCL_VD92
Encyclopedic resources Wikidata; Q54796978
Entry history
Entry creation14-May-2018
Last entry update14-Aug-2025
Version number14