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Cellosaurus Y79-6 (CVCL_VA40)

[Text version]
Cell line name Y79-6
Synonyms Y79c6
Accession CVCL_VA40
Resource Identification Initiative To cite this cell line use: Y79-6 (RRID:CVCL_VA40)
Comments Population: Caucasian.
Misspelling: V79c6; PubMed=2946282.
Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230.
Sequence variations
  • Mutation; HGNC; 9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
Disease Retinoblastoma (NCIt: C7541)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1893 (Y-79)
Sex of cell Female
Age at sampling 2Y6M
Category Cancer cell line

PubMed=2946282; DOI=10.1001/archopht.1986.01050230131048
Rootman J., Gallie B.L., Kumi C., Bussanich N., Rogers B.J., Palcic B.
Ocular penetration, toxicity, and radiosensitization effects of two hypoxic cell radiosensitizers on retinoblastoma.
Arch. Ophthalmol. 104:1693-1697(1986)

Chan H.S.L., Canton M.D., Gallie B.L.
Chemosensitivity and multidrug resistance to antineoplastic drugs in retinoblastoma cell lines.
Anticancer Res. 9:469-474(1989)

PubMed=1682862; DOI=10.1016/S0161-6420(91)32134-1
Chan H.S.L., Thorner P.S., Haddad G., Gallie B.L.
Multidrug-resistant phenotype in retinoblastoma correlates with P-glycoprotein expression.
Ophthalmology 98:1425-1431(1991)

Encyclopedic resources Wikidata; Q54995194
Entry history
Entry creation14-May-2018
Last entry update29-Jun-2023
Version number9