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Cellosaurus Y79-6 (CVCL_VA40)

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Cell line name Y79-6
Synonyms Y79c6
Accession CVCL_VA40
Resource Identification Initiative To cite this cell line use: Y79-6 (RRID:CVCL_VA40)
Comments Population: Caucasian.
Misspelling: V79c6; PubMed=2946282.
Derived from site: In situ; Eye, globe; UBERON=UBERON_0010230.
Sequence variations
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; Ex2-6del; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Unexplicit; IVS20+1G>A; Zygosity=Heterozygous (from parent cell line).
Disease Retinoblastoma (NCIt: C7541)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1893 (Y-79)
Sex of cell Female
Age at sampling 2Y6M
Category Cancer cell line
Publications

PubMed=2946282; DOI=10.1001/archopht.1986.01050230131048
Jack Rootman, Brenda Louise Gallie, Chris Kumi, Nick Bussanich, Brenda J. Rogers, Branko Palcic;
Ocular penetration, toxicity, and radiosensitization effects of two hypoxic cell radiosensitizers on retinoblastoma.
Arch. Ophthalmol. 104:1693-1697(1986)

PubMed=2751270
Helen S.L. Chan, Marc D. Canton, Brenda Louise Gallie;
Chemosensitivity and multidrug resistance to antineoplastic drugs in retinoblastoma cell lines.
Anticancer Res. 9:469-474(1989)

PubMed=1682862; DOI=10.1016/S0161-6420(91)32134-1
Helen S.L. Chan, Paul Scott Thorner, George Haddad, Brenda Louise Gallie;
Multidrug-resistant phenotype in retinoblastoma correlates with P-glycoprotein expression.
Ophthalmology 98:1425-1431(1991)

Cross-references
Encyclopedic resources Wikidata; Q54995194
Entry history
Entry creation14-May-2018
Last entry update19-Dec-2024
Version number10