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Cellosaurus JH-2/TPA (CVCL_V634)

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Cell line name JH-2/TPA
Synonyms JH-2
Accession CVCL_V634
Resource Identification Initiative To cite this cell line use: JH-2/TPA (RRID:CVCL_V634)
Comments Group: Patented cell line.
Registration: International Depositary Authority, China Center for Type Culture Collection; CCTCC C200006.
Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:9051; PLAT.
Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease Fibrosarcoma (NCIt: C3043)
Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0317 (HT-1080)
Sex of cell Male
Age at sampling 35Y
Category Cancer cell line
Publications

Patent=US7632677
Jia-Hui Xia;
Cell line expressing mutated human tissue-type plasminogen activator, the constructing strategy thereof and method of preparing expressed protein.
Patent number US7632677, 15-Dec-2009

Cross-references
Cell line databases/resources cancercelllines; CVCL_V634
CCRID; 4201PAT-CCTCC00148
Encyclopedic resources Wikidata; Q54898623
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number22