Cellosaurus logo
expasy logo

Cellosaurus LNCaP-CS10 (CVCL_V260)

[Text][XML][JSON]
Cell line name LNCaP-CS10
Accession CVCL_V260
Resource Identification Initiative To cite this cell line use: LNCaP-CS10 (RRID:CVCL_V260)
Comments Population: Caucasian.
Characteristics: Androgen-independent (PubMed=19902465).
Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
Sequence variations
  • Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0395 (LNCaP)
Sex of cell Male
Age at sampling 50Y
Category Cancer cell line
Publications

PubMed=19902465; DOI=10.1002/pros.21079
Nobuyuki Ishikura, Hiromitsu Kawata, Ayako Nishimoto, Ryo Nakamura, Nobuya Ishii, Yuko Aoki;
Establishment and characterization of an androgen receptor-dependent, androgen-independent human prostate cancer cell line, LNCaP-CS10.
Prostate 70:457-466(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_V260
Encyclopedic resources Wikidata; Q54902836
Entry history
Entry creation16-Apr-2014
Last entry update10-Apr-2025
Version number16