ID   LNCaP-CS10
AC   CVCL_V260
DR   cancercelllines; CVCL_V260
DR   Wikidata; Q54902836
RX   PubMed=19902465;
CC   Population: Caucasian.
CC   Characteristics: Androgen-independent (PubMed=19902465).
CC   Sequence variation: Mutation; HGNC; HGNC:644; AR; Simple; p.Thr878Ala (c.2632A>G); ClinVar=VCV000009831; Zygosity=Hemizygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:7010; MEN1; Simple; p.Tyr318Ter (c.954T>G) (p.Tyr313Ter, c.939T>A); ClinVar=VCV000439894; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Arg639Ter (c.1915C>T); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Lys6Argfs*4 (c.17_18delAA); ClinVar=VCV000231649; Zygosity=Unspecified (from parent cell line).
CC   Derived from site: Metastatic; Left supraclavicular lymph node; UBERON=UBERON_8480056.
DI   NCIt; C4863; Prostate carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0395 ! LNCaP
SX   Male
AG   50Y
CA   Cancer cell line
DT   Created: 16-04-14; Last updated: 10-04-25; Version: 16
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RX   PubMed=19902465; DOI=10.1002/pros.21079;
RA   Ishikura N., Kawata H., Nishimoto A., Nakamura R., Ishii N., Aoki Y.;
RT   "Establishment and characterization of an androgen receptor-dependent,
RT   androgen-independent human prostate cancer cell line, LNCaP-CS10.";
RL   Prostate 70:457-466(2010).
//