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Cellosaurus CEM cl13 (CVCL_V186)

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Cell line name CEM cl13
Synonyms CEM-CL13; CEM clone 13; CEM-C113; CEM-c113; CEM c113
Accession CVCL_V186
Resource Identification Initiative To cite this cell line use: CEM cl13 (RRID:CVCL_V186)
Comments Population: Caucasian.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: T-cell; CL=CL_0000084.
Sequence variations
  • Gene fusion; HGNC; HGNC:13222; BCL11B + HGNC; HGNC:2488; NKX2-5; Name(s)=NKX2.5-BCL11B (from parent cell line).
  • Mutation; HGNC; HGNC:16712; FBXW7; Simple; p.Arg465Cys (c.1393C>T); ClinVar=VCV000376414; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:3765; FLT3; Simple; p.Ala627Thr (c.1879G>A); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Leu1593_Arg1594insProArgLeuProHisAsnSerSerPheHisPheLeu (c.4780_4781ins36); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7881; NOTCH1; Simple; p.Pro2412Thr (c.7234C>A); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Heterozygous (from parent cell line).
Disease Childhood T acute lymphoblastic leukemia (NCIt: C7953)
Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0207 (CCRF-CEM)
Sex of cell Female
Age at sampling 3Y11M
Category Cancer cell line
Publications

PubMed=2464361; DOI=10.1089/aid.1988.4.441
Olivier Schwartz, Yvette Henin, Valerie Marechal, Luc Montagnier;
A rapid and simple colorimetric test for the study of anti-HIV agents.
AIDS Res. Hum. Retroviruses 4:441-448(1988)

Cross-references
Cell line databases/resources cancercelllines; CVCL_V186
Chemistry resources ChEMBL-Cells; CHEMBL3307394
ChEMBL-Targets; CHEMBL614545
PubChem_Cell_line; CVCL_V186
Encyclopedic resources Wikidata; Q54809246
Entry history
Entry creation16-Apr-2014
Last entry update19-Dec-2024
Version number20