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Cellosaurus PICM-19 (CVCL_V146)

[Text version]
Cell line name PICM-19
Synonyms ARS-PICM-19; Pig Inner Cell Mass-19
Accession CVCL_V146
Resource Identification Initiative To cite this cell line use: PICM-19 (RRID:CVCL_V146)
Comments Group: Space-flown cell line (cellonaut).
Characteristics: Requires feeder cells.
Anecdotal: Have been flown in space on shuttle flight STS-126 to study growth and differentiation in microgravity (PubMed=20333478).
Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107.
Cell type: Hepatocyte; CL=CL_0000182.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Hierarchy Children:
Sex of cell Sex unspecified
Age at sampling 8FD
Category Spontaneously immortalized cell line

PubMed=8354665; DOI=10.1007/BF02634148
Talbot N.C., Rexroad C.E. Jr., Pursel V.G., Powell A.M., Nel N.D.
Culturing the epiblast cells of the pig blastocyst.
In Vitro Cell. Dev. Biol. Anim. 29:543-554(1993)

PubMed=7534591; DOI=10.1007/BF02639394
Talbot N.C., Rexroad C.E. Jr., Powell A.M., Pursel V.G., Caperna T.J., Ogg S.L., Nel N.D.
A continuous culture of pluripotent fetal hepatocytes derived from the 8-day epiblast of the pig.
In Vitro Cell. Dev. Biol. Anim. 30:843-850(1994)

PubMed=8635514; DOI=10.1006/excr.1996.0153
Talbot N.C., Caperna T.J., Lebow L.T., Moscioni A.D., Pursel V.G., Rexroad C.E. Jr.
Ultrastructure, enzymatic, and transport properties of the PICM-19 bipotent liver cell line.
Exp. Cell Res. 225:22-34(1996)

PubMed=12097833; DOI=10.1159/000063704
Talbot N.C., Caperna T.J., Wells K.D.
The PICM-19 cell line as an in vitro model of liver bile ductules: effects of cAMP inducers, biopeptides and pH.
Cells Tissues Organs 171:99-116(2002)

PubMed=20333478; DOI=10.1007/s11626-010-9302-6
Talbot N.C., Caperna T.J., Blomberg L.A., Graninger P.G., Stodieck L.S.
The effects of space flight and microgravity on the growth and differentiation of PICM-19 pig liver stem cells.
In Vitro Cell. Dev. Biol. Anim. 46:502-515(2010)

PubMed=20669140; DOI=10.1177/039139881003300603
Talbot N.C., Caperna T.J., Willard R.R., Meekin J.H., Garrett W.M.
Characterization of two subpopulations of the PICM-19 porcine liver stem cell line for use in cell-based extracorporeal liver assistance devices.
Int. J. Artif. Organs 33:348-361(2010)

PubMed=23148238; DOI=10.2527/jas.2012-5748
Talbot N.C., Caperna T.J., Garrett W.M.
Growth and development symposium: development, characterization, and use of a porcine epiblast-derived liver stem cell line: ARS-PICM-19.
J. Anim. Sci. 91:66-77(2013)

Encyclopedic resources Wikidata; Q54947385
Entry history
Entry creation16-Apr-2014
Last entry update29-Jun-2023
Version number10