ID   PICM-19
AC   CVCL_V146
SY   ARS-PICM-19; Pig Inner Cell Mass-19
DR   Wikidata; Q54947385
RX   PubMed=7534591;
RX   PubMed=8354665;
RX   PubMed=8635514;
RX   PubMed=12097833;
RX   PubMed=20333478;
RX   PubMed=20669140;
RX   PubMed=23148238;
CC   Group: Space-flown cell line (cellonaut).
CC   Characteristics: Requires feeder cells.
CC   Anecdotal: Have been flown in space on shuttle flight STS-126 to study growth and differentiation in microgravity (PubMed=20333478).
CC   Derived from site: In situ; Fetal liver; UBERON=UBERON_0002107.
CC   Cell type: Hepatocyte; CL=CL_0000182.
OX   NCBI_TaxID=9823; ! Sus scrofa (Pig)
SX   Sex unspecified
AG   8FD
CA   Spontaneously immortalized cell line
DT   Created: 16-04-14; Last updated: 29-06-23; Version: 10
CH   CVCL_5T67 ! PICM-19B
CH   CVCL_5T69 ! PICM-19FF
CH   CVCL_5T68 ! PICM-19H
//
RX   PubMed=20333478; DOI=10.1007/s11626-010-9302-6;
RA   Talbot, Neil C.
RA   Caperna, Thomas J.
RA   Blomberg, Le Ann
RA   Graninger, Paul G.
RA   Stodieck, Louis S.
RT   "The effects of space flight and microgravity on the growth and
RT   differentiation of PICM-19 pig liver stem cells.";
RL   In Vitro Cell. Dev. Biol. Anim. 46:502-515(2010).
//
RX   PubMed=8635514; DOI=10.1006/excr.1996.0153;
RA   Talbot, Neil C.
RA   Caperna, Thomas J.
RA   Lebow, Laura T.
RA   Moscioni, Albert David
RA   Pursel, Vernon George
RA   Rexroad, Caird Eugene Jr.
RT   "Ultrastructure, enzymatic, and transport properties of the PICM-19
RT   bipotent liver cell line.";
RL   Exp. Cell Res. 225:22-34(1996).
//
RX   PubMed=23148238; DOI=10.2527/jas.2012-5748;
RA   Talbot, Neil C.
RA   Caperna, Thomas J.
RA   Garrett, Wesley Macdougall
RT   "Growth and development symposium: development, characterization, and
RT   use of a porcine epiblast-derived liver stem cell line: ARS-PICM-19.";
RL   J. Anim. Sci. 91:66-77(2013).
//
RX   PubMed=12097833; DOI=10.1159/000063704;
RA   Talbot, Neil C.
RA   Caperna, Thomas J.
RA   Wells, Kevin D.
RT   "The PICM-19 cell line as an in vitro model of liver bile ductules:
RT   effects of cAMP inducers, biopeptides and pH.";
RL   Cells Tissues Organs 171:99-116(2002).
//
RX   PubMed=7534591; DOI=10.1007/BF02639394;
RA   Talbot, Neil C.
RA   Rexroad, Caird Eugene Jr.
RA   Powell, Anne M.
RA   Pursel, Vernon George
RA   Caperna, Thomas J.
RA   Ogg, Sherry L.
RA   Nel, Neil D.
RT   "A continuous culture of pluripotent fetal hepatocytes derived from
RT   the 8-day epiblast of the pig.";
RL   In Vitro Cell. Dev. Biol. Anim. 30:843-850(1994).
//
RX   PubMed=20669140; DOI=10.1177/039139881003300603;
RA   Talbot, Neil C.
RA   Caperna, Thomas J.
RA   Willard, Ryan R.
RA   Meekin, John H.
RA   Garrett, Wesley Macdougall
RT   "Characterization of two subpopulations of the PICM-19 porcine liver
RT   stem cell line for use in cell-based extracorporeal liver assistance
RT   devices.";
RL   Int. J. Artif. Organs 33:348-361(2010).
//
RX   PubMed=8354665; DOI=10.1007/BF02634148;
RA   Talbot, Neil C.
RA   Rexroad, Caird Eugene Jr.
RA   Pursel, Vernon George
RA   Powell, Anne M.
RA   Nel, Neil D.
RT   "Culturing the epiblast cells of the pig blastocyst.";
RL   In Vitro Cell. Dev. Biol. Anim. 29:543-554(1993).
//