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Cellosaurus (CVCL_V009)

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Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Caucasian.
Transformant: NCBI_TaxID; 37296; Human herpesvirus 8 (HHV-8/KSHV).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq virome analysis.
Omics: Transcriptomics; RNAseq.
Omics: Variations; Array-based CGH.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (PubMed=19608668).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met246Val (c.736A>G); ClinVar=VCV000100815; Zygosity=Heterozygous (PubMed=19608668).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asp259Asn (c.775G>A); Zygosity=Heterozygous (PubMed=19608668; DepMap=ACH-000923).
HLA typing Source: PubMed=26589293
Class I
HLA-AA*24:02,68:01
HLA-BB*38:01,44:02
HLA-CC*05:01,12:03
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.81
Native American0.07
East Asian, North2
East Asian, South0.6
South Asian8.1
European, North24.92
European, South62.51
Disease Primary effusion lymphoma (NCIt: C6915)
Primary effusion lymphoma (ORDO: Orphanet_48686)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 94Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-2294

Markers:
AmelogeninX
CSF1PO10
D2S133823,24
D3S135816,17
D5S81812
D7S82010,11
D8S117914
D13S31711,13
D16S53910,11
D18S5113,17
D19S43314,15
D21S1128,31.2
FGA20,22.2
Penta D8,13
Penta E10
TH017,9
TPOX8,9
vWA17,18

Run an STR similarity search on this cell line
Web pages Info; COPE; -; http://www.cells-talk.com/index.php/page/copelibrary?key=BCP-1
Info; Wikipedia; -; https://en.wikipedia.org/wiki/BCP-1_cells
Publications





Lelita A. Yakovleva;
Herpesvirus HVMA: a new representative in the group of the EBV-like B-lymphotropic herpesviruses of primates.
Haematol. Blood Transfus. 29:312-313(1985)


Harry W. Findley Jr., Lu-Bing Gu, Andrew M. Yeager, Mu-Xiang Zhou;
Expression and regulation of Bcl-2, Bcl-xl, and Bax correlate with p53 status and sensitivity to apoptosis in childhood acute lymphoblastic leukemia.
Blood 89:2986-2993(1997)


Luigi Del Vecchio;
JURL-MK1 (c-kit(high)/CD30-/CD40-) and JURL-MK2 (c-kit(low)/CD30+/CD40+) cell lines: 'two-sided' model for investigating leukemic megakaryocytopoiesis.
Leukemia 11:1554-1564(1997)




J. Virol. 76:11291-11300(2002)


Matthias Lenk, Thomas Christoph Mettenleiter;
Functional analysis of the pseudorabies virus UL51 protein.
J. Virol. 79:3831-3840(2005)


Yusuke Furukawa, Tomokatsu Ikawa, Hiroshi Kawamoto, S. Helen Oram, Berthold Gottgens, Nobutaka Kiyokawa, Yoshitaka Miyagawa, Hajime Okita, Koshi Akahane, Xiao-Chun Zhang, Itaru Kuroda ...Show all 19 authors... , Hiroko Honna, Keiko Kagami, Kumiko Goi, Hidemitsu Kurosawa, Alfred Thomas Look, Hirotaka Matsui, Toshiya Inaba, Kanji Sugita; Show fewer authors
Aberrant induction of LMO2 by the E2A-HLF chimeric transcription factor and its implication in leukemogenesis of B-precursor ALL with t(17;19).
Blood 116:962-970(2010)


Julie Adam, Ann Hedley, Gabriela Kalna, Ian Philip Mark Tomlinson, Patrick John Pollard, David George Watson, Ralph J. DeBerardinis, Tomer Shlomi, Eytan Ruppin, Eyal Gottlieb;
Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase.
Nature 477:225-228(2011)



arenaviruses, the etiological agents of boid inclusion body disease.
J. Virol. 87:10918-10935(2013)


Hangnoh Lee, Charles Joel McManus, Dong-Yeon Cho, Matthew Eaton, Fioranna Renda, Maria Patrizia Somma, Lucy Cherbas, Gemma May, Sara Powell, Da-Yu Zhang, Li-Jun Zhan ...Show all 20 authors... , Alissa Resch, Justen Andrews, Susan E. Celniker, Peter Cherbas, Teresa Maria Przytycka, Maurizio Gatti, Brian Oliver, Brenton R. Graveley, David M. MacAlpine; Show fewer authors
DNA copy number evolution in Drosophila cell lines.
Genome Biol. 15:R70.1-R70.20(2014)




BMC Cancer 15:240.1-240.16(2015)



literature.
Cancer Res. 77:2784-2788(2017)


Tetsuhiro Kikuchi, Asuka Morizane, Daisuke Doi, Hiroaki Magotani, Hirotaka Onoe, Takuya Hayashi, Hiroshi Mizuma, Sayuki Takara, Ryosuke Takahashi, Haruhisa Inoue, Satoshi Morita ...Show all 16 authors... , Michio Yamamoto, Keisuke Okita, Masato Nakagawa, Malin Parmar, Jun Takahashi; Show fewer authors
Human iPS cell-derived dopaminergic neurons function in a primate Parkinson's disease model.
Nature 548:592-596(2017)

Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number31